The regulatory role of IL-10 in neurodegenerative diseases

C Porro, A Cianciulli, MA Panaro - Biomolecules, 2020 - mdpi.com
IL-10, an immunosuppressive cytokine, is considered an important anti-inflammatory
modulator of glial activation, preventing inflammation-mediated neuronal degeneration …

Induction of interleukin-10 producing dendritic cells as a tool to suppress allergen-specific T helper 2 responses

S Schülke - Frontiers in immunology, 2018 - frontiersin.org
Dendritic cells (DCs) are gatekeepers of the immune system that control induction and
polarization of primary, antigen-specific immune responses. Depending on their …

Advances in HPV‐associated tumor management: therapeutic strategies and emerging insights

X Gong, H Chi, Z Xia, G Yang… - Journal of Medical …, 2023 - Wiley Online Library
With the rapid increase in the incidence of cervical cancer, anal cancer and other cancers,
human papillomavirus (HPV) infection has become a growing concern. Persistent infection …

[PDF][PDF] Epidemiology and prevention of Human Papillomavirus

I Manini, E Montomoli - Ann Ig, 2018 - researchgate.net
Human papillomavirus is the most common sexually transmitted infection, and skin-to-skin
genital contact is sufficient for virus transmission. Cervical cancer is the second-most …

Dysregulated tumor-associated macrophages in carcinogenesis, progression and targeted therapy of gynecological and breast cancers

T Xu, S Yu, J Zhang, S Wu - Journal of hematology & oncology, 2021 - Springer
Gynecological and breast cancers are a group of heterogeneous malignant tumors.
Although existing treatment strategies have ameliorated the clinical outcomes of patients …

TGF-β1 suppresses the T-cell response in teleost fish by initiating Smad3-and Foxp3-mediated transcriptional networks

Q Zhang, M Geng, K Li, H Gao, X Jiao, K Ai… - Journal of Biological …, 2023 - ASBMB
Transforming growth factor-β1 (TGF-β1) can suppress the activation, proliferation, and
function of many T-cell subsets, protecting organisms from inflammatory and autoimmune …

Research progress on tumor‐associated macrophages and inflammation in cervical cancer

Y Liu, L Li, Y Li, X Zhao - BioMed research international, 2020 - Wiley Online Library
Cervical cancer is the most common gynecological tumor worldwide. Persistent infection of
high‐risk HPV‐induced smouldering inflammation is considered to be an important risk …

IL-10 negatively controls the primary T cell response of tilapia by triggering the JAK1/STAT3/SOCS3 axis that suppresses NF-κB and MAPK/ERK signaling

K Li, J Li, X Wei, J Wang, M Geng, K Ai… - The Journal of …, 2023 - journals.aai.org
The braking mechanisms to protect the host from tissue damage and inflammatory disease
caused by an overexuberant immune response are common in many T cell subsets …

The host-microbe interplay in human papillomavirus-induced carcinogenesis

R Wakabayashi, Y Nakahama, V Nguyen, JL Espinoza - Microorganisms, 2019 - mdpi.com
Every year nearly half a million new cases of cervix cancer are diagnosed worldwide,
making this malignancy the fourth commonest cancer in women. In 2018, more than 270,000 …

[HTML][HTML] Therapeutic strategies of different HPV status in head and neck squamous cell carcinoma

Y Sun, Z Wang, S Qiu, R Wang - International Journal of Biological …, 2021 - ncbi.nlm.nih.gov
Head and neck squamous cell carcinoma (HNSCC) is the 9 th most common malignant
tumor in the world. Based on the etiology, HNSCC has two main subtypes: human …