Closing the loop in psychiatric deep brain stimulation: physiology, psychometrics, and plasticity
AS Widge - Neuropsychopharmacology, 2024 - nature.com
Deep brain stimulation (DBS) is an invasive approach to precise modulation of
psychiatrically relevant circuits. Although it has impressive results in open-label psychiatric …
psychiatrically relevant circuits. Although it has impressive results in open-label psychiatric …
Introduction to the special issue on the neurobiology of human fear and anxiety
MA Fullana, AJ Shackman - Neuroscience & Biobehavioral Reviews, 2023 - Elsevier
Pathological fear and anxiety are a leading cause of human misery and morbidity, afflicting
millions of individuals worldwide. Yet existing treatments are inconsistently effective or …
millions of individuals worldwide. Yet existing treatments are inconsistently effective or …
Fear extinction rescuing effects of dopamine and L-DOPA in the ventromedial prefrontal cortex
SB Sartori, TMV Keil, KK Kummer, CP Murphy… - Translational …, 2024 - nature.com
The ventromedial prefrontal cortex (vmPFC; rodent infralimbic cortex (IL)), is posited to be an
important locus of fear extinction-facilitating effects of the dopamine (DA) bio-precursor, L …
important locus of fear extinction-facilitating effects of the dopamine (DA) bio-precursor, L …
[HTML][HTML] Intermittent theta burst stimulation of the left dorsolateral prefrontal cortex has no additional effect on the efficacy of virtual reality exposure therapy for …
B Bohmeier, LM Cybinski, D Gromer, D Bellinger… - Behavioural Brain …, 2024 - Elsevier
Anxiety disorders are among the most common mental disorders. Treatment guidelines
recommend pharmacotherapy and cognitive behavioral therapy as standard treatment …
recommend pharmacotherapy and cognitive behavioral therapy as standard treatment …
Prefrontal Dopamine in Flexible Adaptation to Environmental Changes: A Game for Two Players
Deficits in cognitive flexibility have been characterized in affective, anxiety, and
neurodegenerative disorders. This paper reviews data, mainly from studies on animal …
neurodegenerative disorders. This paper reviews data, mainly from studies on animal …
Integrating Threat Conditioning and the Hierarchical Taxonomy of Psychopathology (HiTOP) to Advance the Study of Anxiety-Related Psychopathology
Theoretical and methodological research on threat conditioning provides important
neuroscience-informed approaches to studying fear and anxiety. The conditioning …
neuroscience-informed approaches to studying fear and anxiety. The conditioning …
Causally probing the role of the human hippocampus in fear discrimination: A precision functional mapping guided TMS study in individuals with post-traumatic stress …
Fear overgeneralization is a potential pathogenic mechanism of anxiety-related disorders. A
dominant model posits that overgeneralization occurs when the hippocampus fails to …
dominant model posits that overgeneralization occurs when the hippocampus fails to …
[PDF][PDF] Anxiety, Neuroscience and Biobehavioral Reviews,(2023)
MA Fullana, AJ Shackman - shackmanlab.org
Pathological fear and anxiety are a leading cause of human misery and morbidity, afflicting
millions of individuals worldwide. Yet existing treatments are inconsistently effective or …
millions of individuals worldwide. Yet existing treatments are inconsistently effective or …