Learning Objectives Assess the basic aspects of PNET tumor biology, pathogenesis, and
classification. Explain the epidemiology and evaluate the prognosis of PNET patients …

Gastroenteropancreatic neuroendocrine tumors (GEP-NETs) are a heterogeneous group of
neoplasms that arise from cells of the diffuse neuroendocrine system and are characterized …

Gastrinomas are neuroendocrine neoplasms, usually located in the duodenum or pancreas,
that secrete gastrin and cause a clinical syndrome known as Zollinger-Ellison syndrome …

Abstract Gastro-entero-pancreatic (GEP) neuroendocrine tumors (NETs) are rare
neoplasms, although their prevalence has increased substantially over the past three …

Background The incidence of neuroendocrine tumours (NET) has increased over the past
three decades. Hepatic metastases which occur in up to 75% of NET patients significantly …

Now in its seventh edition, this highly-regarded book is designed as an introductory and
reference text on the principles of diagnosis, staging, and treatment of tumors. As for the last …

Neuroendocrine tumors (NETs) are tumors that arise from the diffuse endocrine system.
They are slow-growing and capable of storing and secreting different peptides and …

Clinical trials indicate efficacy of drugs inhibiting the mammalian target of rapamycin (mTOR)
in the treatment of gastroenteropancreatic neuroendocrine tumours (GEP-NET); however …

Pancreatic neuroendocrine tumors (PNETs) are neoplasms that arise from the hormone
producing cells of the islets of Langerhans, also known as pancreatic islet cells. PNETs are …

The mechanistic target of rapamycin (mTOR) is part of the phosphoinositide-3-kinase
(PI3K)/protein kinase B (AkT)/mTOR pathway and owes its name to the inhibitory effect of …