Microfluidics for drug development: from synthesis to evaluation

Y Liu, L Sun, H Zhang, L Shang, Y Zhao - Chemical reviews, 2021 - ACS Publications
Drug development is a long process whose main content includes drug synthesis, drug
delivery, and drug evaluation. Compared with conventional drug development procedures …

PLGA-based nanoparticles in cancer treatment

S Rezvantalab, NI Drude, MK Moraveji… - Frontiers in …, 2018 - frontiersin.org
Nanomedicines can be used for a variety of cancer therapies including tumor-targeted drug
delivery, hyperthermia, and photodynamic therapy. Poly (lactic-co-glycolic acid)(PLGA) …

PLGA-based nanomedicine: history of advancement and development in clinical applications of multiple diseases

HO Alsaab, FD Alharbi, AS Alhibs, NB Alanazi… - Pharmaceutics, 2022 - mdpi.com
Research on the use of biodegradable polymers for drug delivery has been ongoing since
they were first used as bioresorbable surgical devices in the 1980s. For tissue engineering …

Nano delivery of chemotherapeutic ICD inducers for tumor immunotherapy

J Guo, Y Zou, L Huang - Small Methods, 2023 - Wiley Online Library
Immunogenic cell death (ICD, also known as immunogenic apoptosis) of malignant cells is
confirmed to activate the host immune system to prevent, control, and eliminate tumors …

Microfluidic methods for fabrication and engineering of nanoparticle drug delivery systems

L Zhang, Q Chen, Y Ma, J Sun - ACS Applied Bio Materials, 2019 - ACS Publications
Microfluidic technologies with precise fluid control and rapid microscale mixing have
attracted widespread interest in the fabrication and engineering of nanomaterials for drug …

[HTML][HTML] Engineered tumor cell-derived vaccines against cancer: The art of combating poison with poison

X Zhang, H Cui, W Zhang, Z Li, J Gao - Bioactive Materials, 2023 - Elsevier
Tumor vaccination is a promising approach for tumor immunotherapy because it presents
high specificity and few side effects. However, tumor vaccines that contain only a single …

Properties of poly (lactic-co-glycolic acid) and progress of poly (lactic-co-glycolic acid)-based biodegradable materials in biomedical research

Y Lu, D Cheng, B Niu, X Wang, X Wu, A Wang - Pharmaceuticals, 2023 - mdpi.com
In recent years, biodegradable polymers have gained the attention of many researchers for
their promising applications, especially in drug delivery, due to their good biocompatibility …

Microfluidics for biomedical analysis

Y Yang, Y Chen, H Tang, N Zong, X Jiang - Small methods, 2020 - Wiley Online Library
Many new techniques and materials have been applied to microfluidic systems in the past
decade, and integrated microfluidic chips have become powerful platforms for realizing …

Microfluidics‐based biomaterials and biodevices

R Dong, Y Liu, L Mou, J Deng, X Jiang - Advanced Materials, 2019 - Wiley Online Library
The rapid development of microfluidics technology has promoted new innovations in
materials science, particularly by interacting with biological systems, based on precise …

Multiphase flow in microfluidics: From droplets and bubbles to the encapsulated structures

A Sattari, P Hanafizadeh, M Hoorfar - Advances in Colloid and Interface …, 2020 - Elsevier
Microfluidic technologies have a unique ability to control more precisely and effectively on
two-phase flow systems in comparison with macro systems. Controlling the size of the …