Obstructive sleep apnoea heterogeneity and cardiovascular disease

S Redline, A Azarbarzin, Y Peker - Nature Reviews Cardiology, 2023 - nature.com
Obstructive sleep apnoea (OSA), characterized by recurrent periods of upper airway
obstruction and intermittent hypoxaemia, is prevalent in patients with cardiovascular disease …

[HTML][HTML] Role of precision medicine in obstructive sleep apnoea

Y Liu, AA Ghafoor, M Hajipour, N Ayas - BMJ medicine, 2023 - ncbi.nlm.nih.gov
Obstructive sleep apnoea is a substantial clinical and public health problem because it
contributes to harmful effects on quality of life, daytime symptoms, road traffic incidents, and …

[HTML][HTML] Hypoxic burden to guide CPAP treatment allocation in patients with obstructive sleep apnoea: a post hoc study of the ISAACC trial

L Pinilla, N Esmaeili, G Labarca… - European …, 2023 - Eur Respiratory Soc
Background Hypoxic burden (HB) has emerged as a strong predictor of cardiovascular risk
in obstructive sleep apnoea (OSA). We aimed to assess the potential of HB to predict the …

Hypoxic burden based on automatically identified desaturations is associated with adverse health outcomes

N Esmaeili, G Labarca, WH Hu, D Vena… - Annals of the …, 2023 - atsjournals.org
Rationale: Recent studies have shown that sleep apnea–specific intermittent hypoxemia
quantified by the hypoxic burden (HB) predicted cardiovascular disease (CVD)–related …

Treatment of Sleep Apnea and Reduction in Blood Pressure: The Role of Heart Rate Response and Hypoxic Burden

L Messineo, SA Sands, C Schmickl, G Labarca… - …, 2024 - Am Heart Assoc
BACKGROUND: Obstructive sleep apnea is associated with increased blood pressure (BP).
Obstructive sleep apnea treatment reduces BP with substantial variability, not explained by …

Association between undiagnosed obstructive sleep apnea and severe course of COVID-19: a prospective observational study

N Celejewska-Wójcik, K Polok, K Górka, T Stachura… - Sleep and …, 2024 - Springer
Purpose Obstructive sleep apnea (OSA) is associated with many long-term health
consequences. We hypothesized that previously unrecognized and untreated OSA may be …

Measuring severity in OSA: the arguments for collaboratively developing a multidimensional score

MÁ Martínez-García, G Oscullo… - Journal of Clinical …, 2023 - jcsm.aasm.org
Respiratory disorders are complex and heterogeneous conditions, particularly as it relates to
their clinical presentation. 1 One of the major implications of such phenotypic heterogeneity …

The use of the sleep apnea-specific hypoxic burden to predict obstructive sleep apnea hypopnea syndrome: evidence from a large cross-sectional study

C Li, Y Gao, W Huang, H Xu, Y Liu, J Zou, H Zhu, X Li… - Sleep Medicine, 2023 - Elsevier
Objectives Obstructive sleep apnea hypopnea syndrome (OSA) is an independent risk factor
for neurocognitive and behavioral problems and cardiovascular and metabolic morbidities …

Overview of the hypnodensity approach to scoring sleep for polysomnography and home sleep testing

P Anderer, M Ross, A Cerny, R Vasko, E Shaw… - Frontiers in …, 2023 - frontiersin.org
Human experts scoring sleep according to the American Academy of Sleep Medicine
(AASM) rules are forced to select, for every 30-second epoch, one out of five stages, even if …

Diagnosis and Treatment of Sleep Apnea in Children: A Future Perspective Is Needed

E Solano-Pérez, C Coso, M Castillo-García… - Biomedicines, 2023 - mdpi.com
Obstructive sleep apnea (OSA) in children is a prevalent, but still, today, underdiagnosed
illness, which consists of repetitive episodes of upper airway obstruction during sleep with …