Pathogenesis of pneumonia and acute lung injury

ME Long, RK Mallampalli, JC Horowitz - Clinical Science, 2022 - portlandpress.com
Pneumonia and its sequelae, acute lung injury, present unique challenges for pulmonary
and critical care healthcare professionals, and these challenges have recently garnered …

Hypertension, the renin–angiotensin system, and the risk of lower respiratory tract infections and lung injury: implications for COVID-19: European Society of …

R Kreutz, EAEH Algharably, M Azizi… - Cardiovascular …, 2020 - academic.oup.com
Systemic arterial hypertension (referred to as hypertension herein) is a major risk factor of
mortality worldwide, and its importance is further emphasized in the context of the novel …

Definition, causes, pathogenesis, and consequences of chronic obstructive pulmonary disease exacerbations

AI Ritchie, JA Wedzicha - Clinics in chest medicine, 2020 - chestmed.theclinics.com
Acute exacerbations of chronic obstructive pulmonary disease (AECOPDs) are episodes of
symptom worsening 1 that have significant adverse consequences for patients. 2 The …

European Respiratory Society guidelines for the management of adult bronchiectasis

E Polverino, PC Goeminne… - European …, 2017 - Eur Respiratory Soc
Bronchiectasis in adults is a chronic disorder associated with poor quality of life and frequent
exacerbations in many patients. There have been no previous international guidelines. The …

The REMAP-CAP (randomized embedded multifactorial adaptive platform for community-acquired pneumonia) study. Rationale and design

DC Angus, S Berry, RJ Lewis, F Al-Beidh… - Annals of the …, 2020 - atsjournals.org
There is broad interest in improved methods to generate robust evidence regarding best
practice, especially in settings where patient conditions are heterogenous and require …

Fast multiplex bacterial PCR of bronchoalveolar lavage for antibiotic stewardship in hospitalised patients with pneumonia at risk of Gram-negative bacterial infection …

AM Darie, N Khanna, K Jahn, M Osthoff… - The Lancet …, 2022 - thelancet.com
Background PCR-based testing has transformed the management of suspected respiratory
viral infections. We aimed to determine whether multiplex bacterial PCR of bronchoalveolar …

[HTML][HTML] Optimizing antibiotic therapies to reduce the risk of bacterial resistance

S Bassetti, S Tschudin-Sutter, A Egli… - European journal of …, 2022 - Elsevier
The incidence of infections caused by bacteria that are resistant to antibiotics is constantly
increasing. In Europe alone, it has been estimated that each year about 33′ 000 deaths are …

Legionnaires' disease: update on diagnosis and treatment

D Viasus, V Gaia, C Manzur-Barbur… - Infectious Diseases and …, 2022 - Springer
Legionellosis is the infection caused by bacteria of the genus Legionella, including a non-
pneumonic influenza-like syndrome, and Legionnaires' disease is a more serious illness …

Scope, quality, and inclusivity of clinical guidelines produced early in the covid-19 pandemic: rapid review

A Dagens, L Sigfrid, E Cai, S Lipworth, V Cheng… - bmj, 2020 - bmj.com
Objective To appraise the availability, quality, and inclusivity of clinical guidelines produced
in the early stage of the coronavirus disease 2019 (covid-19) pandemic. Design Rapid …

Colonic diverticular disease

A Tursi, C Scarpignato, LL Strate, A Lanas… - Nature Reviews …, 2020 - nature.com
Diverticula are outpouchings of the intestinal wall and are common anatomical alterations
detected in the human colon. Colonic diverticulosis (the presence of diverticula in the colon; …