Overview of the 2022 WHO classification of neuroendocrine neoplasms

G Rindi, O Mete, S Uccella, O Basturk, S La Rosa… - Endocrine …, 2022 - Springer
In this review, we detail the changes and the relevant features that are applied to
neuroendocrine neoplasms (NENs) in the 2022 WHO Classification of Endocrine and …

[HTML][HTML] The diagnosis and clinical significance of paragangliomas in unusual locations

SL Asa, S Ezzat, O Mete - Journal of clinical medicine, 2018 - mdpi.com
Paragangliomas are neuroendocrine neoplasms, derived from paraganglia of the
sympathetic and parasympathetic nervous systems. They are most commonly identified in …

[HTML][HTML] Principles of diagnosis and management of neuroendocrine tumours

MJ Raphael, DL Chan, C Law, S Singh - Cmaj, 2017 - Can Med Assoc
Differentiation refers to how closely the neoplastic cells resemble their nonneoplastic
counterparts in the tissue from which they arose. Well-differentiated cancer cells closely …

[HTML][HTML] Angiogenesis in pancreatic cancer: pre-clinical and clinical studies

T Annese, R Tamma, S Ruggieri, D Ribatti - Cancers, 2019 - mdpi.com
Angiogenesis is a crucial event in tumor development and progression, occurring by
different mechanisms and it is driven by pro-and anti-angiogenic molecules. Pancreatic …

[HTML][HTML] A Delphic consensus assessment: imaging and biomarkers in gastroenteropancreatic neuroendocrine tumor disease management

K Oberg, E Krenning, A Sundin, L Bodei… - Endocrine …, 2016 - ec.bioscientifica.com
The complexity of the clinical management of neuroendocrine neoplasia (NEN) is
exacerbated by limitations in imaging modalities and a paucity of clinically useful …

Management of small bowel neuroendocrine tumors

AT Scott, JR Howe - Journal of oncology practice, 2018 - ascopubs.org
Small bowel neuroendocrine tumors (NETs) are increasing in incidence and are now the
most common primary malignancies of the small intestine. Despite this increase, the vague …

[HTML][HTML] Identification of functional pathways and molecular signatures in neuroendocrine neoplasms by multi-omics analysis

V Melone, A Salvati, D Palumbo, G Giurato… - Journal of translational …, 2022 - Springer
Abstract Background Neuroendocrine neoplasms (NENs) represent a heterogeneous class
of rare tumors with increasing incidence. They are characterized by the ability to secrete …

Therapeutic options for neuroendocrine tumors: a systematic review and network meta-analysis

RM Kaderli, M Spanjol, A Kollár, L Bütikofer… - JAMA …, 2019 - jamanetwork.com
Importance Multiple therapies are currently available for patients with neuroendocrine
tumors (NETs), yet many therapies have not been compared head-to-head within …

Treatment of symptomatic neuroendocrine tumor syndromes: recent advances and controversies

T Ito, L Lee, RT Jensen - Expert opinion on pharmacotherapy, 2016 - Taylor & Francis
ABSTRACT Introduction: Neuroendocrine tumors (NETs), once thought rare, are increasing
in frequency in most countries and receiving increasing-attention. NETs present two …

Assessment of NETest Clinical utility in a US Registry‐based study

E Liu, S Paulson, A Gulati, J Freudman, W Grosh… - The …, 2019 - academic.oup.com
Background The clinical relevance of molecular biomarkers in oncology management has
been recognized in breast and lung cancers. We evaluated a blood‐based multigene assay …