Collagen architecture and signaling orchestrate cancer development

H Su, M Karin - Trends in cancer, 2023 - cell.com
The tumor microenvironment (TME) controls tumor progression and maintenance.
Accordingly, tumor-centric cancer treatment must adjust to being more holistic and TME …

[HTML][HTML] Crosstalk between macrophages and cardiac cells after myocardial infarction

Y Jian, X Zhou, W Shan, C Chen, W Ge, J Cui… - Cell Communication and …, 2023 - Springer
Cardiovascular diseases, such as myocardial infarction (MI), are a leading cause of death
worldwide. Acute MI (AMI) inflicts massive injury to the coronary microcirculation, causing …

[HTML][HTML] Inflammation in myocardial ischemia/reperfusion injury: underlying mechanisms and therapeutic potential

J Francisco, DP Del Re - Antioxidants, 2023 - mdpi.com
Acute myocardial infarction (MI) occurs when blood flow to the myocardium is restricted,
leading to cardiac damage and massive loss of viable cardiomyocytes. Timely restoration of …

[HTML][HTML] Resolvin D2 and its receptor GPR18 in cardiovascular and metabolic diseases: A promising biomarker and therapeutic target

M Zhao, Z Zheng, Z Yin, J Zhang, J Qin, J Wan… - Pharmacological …, 2023 - Elsevier
Accumulating evidence suggests that inflammation plays an important role in the
pathophysiology of the initiation and progression of cardiovascular and metabolic diseases …

NETosis: sculpting tumor metastasis and immunotherapy

Y Hu, H Wang, Y Liu - Immunological Reviews, 2024 - Wiley Online Library
The process of neutrophil extracellular traps (NETs) formation, called NETosis, is a peculiar
death modality of neutrophils, which was first observed as an immune response against …

Impact of reperfusion on temporal immune cell dynamics after myocardial infarction

RYK Zhang, BJ Cochran, SR Thomas… - Journal of the American …, 2023 - Am Heart Assoc
Excessive inflammation and impaired healing of cardiac tissue following a myocardial
infarction (MI) can drive the development of heart failure. Cardiac repair begins immediately …

[HTML][HTML] The regulatory mechanism of neutrophil extracellular traps in cancer biological behavior

H Wang, Y Zhang, Q Wang, X Wei, H Wang, K Gu - Cell & Bioscience, 2021 - Springer
As the predominant host defense against pathogens, neutrophil extracellular traps (NETs)
have attracted increasing attention due to their vital roles in infectious inflammation in the …

Visfatin aggravates transverse aortic constriction‐induced cardiac remodelling by enhancing macrophage‐mediated oxidative stress in mice

C Shen, R Fang, J Wang, N Wu, S Wang… - Journal of Cellular …, 2023 - Wiley Online Library
Previous studies have reported that visfatin can regulate macrophage polarisation, which
has been demonstrated to participate in cardiac remodelling. The aims of this study were to …

DEL-1 deficiency aggravates pressure overload-induced heart failure by promoting neutrophil infiltration and neutrophil extracellular traps formation

M Zhao, Z Zheng, Z Yin, J Zhang, S Peng, J Liu… - Biochemical …, 2023 - Elsevier
Recent studies have shown that neutrophils play an important role in the development and
progression of heart failure. Developmental endothelial locus-1 (DEL-1) is an anti …

[HTML][HTML] Interaction between neutrophil extracellular traps and cardiomyocytes contributes to atrial fibrillation progression

L He, R Liu, H Yue, X Zhang, X Pan, Y Sun… - … and Targeted Therapy, 2023 - nature.com
Atrial fibrillation (AF) is a frequent arrhythmia associated with cardiovascular morbidity and
mortality. Neutrophil extracellular traps (NETs) are DNA fragments with cytoplasm proteins …