3D printing in pharmaceutics: A new tool for designing customized drug delivery systems

J Goole, K Amighi - International journal of pharmaceutics, 2016 - Elsevier
Three-dimensional printing includes a wide variety of manufacturing techniques, which are
all based on digitally-controlled depositing of materials (layer-by-layer) to create freeform …

Formulation approaches to pediatric oral drug delivery: benefits and limitations of current platforms

FL Lopez, TB Ernest, C Tuleu… - Expert opinion on drug …, 2015 - Taylor & Francis
Introduction: Most conventional drug delivery systems are not acceptable for pediatric
patients as they differ in their developmental status and dosing requirements from other …

Oral films: current status and future perspectives: I—galenical development and quality attributes

AF Borges, C Silva, JFJ Coelho, S Simões - Journal of Controlled Release, 2015 - Elsevier
Polymers are the most common excipients used in pharmaceutical dosage forms, and often
new applications and innovative polymers appear aiming to overcome unmet needs in the …

Fast dissolving oral drug delivery system based on electrospun nanofibrous webs of cyclodextrin/ibuprofen inclusion complex nanofibers

A Celebioglu, T Uyar - Molecular pharmaceutics, 2019 - ACS Publications
In this study, the polymer-free electrospinning was performed in order to produce
cyclodextrin/ibuprofen inclusion complex nanofibers, which could have potential as the fast …

[HTML][HTML] Orodispersible polymer films with the poorly water-soluble drug, olanzapine: hot-melt pneumatic extrusion for single-process 3D printing

HW Cho, SH Baek, BJ Lee, HE Jin - Pharmaceutics, 2020 - mdpi.com
Amorphous solid dispersions (ASDs) improve the oral delivery of poorly water-soluble
drugs. ASDs of olanzapine (OLZ), which have a high melting point and low solubility, are …

[HTML][HTML] An insight into preparatory methods and characterization of orodispersible film—A review

A Salawi - Pharmaceuticals, 2022 - mdpi.com
Over the past few decades, researchers and companies have been trying to develop novel
drug delivery systems to ensure safety, efficacy, compliance, and patient acceptability …

Overview and future potential of buccal mucoadhesive films as drug delivery systems for biologics

M Montenegro-Nicolini, JO Morales - Aaps Pharmscitech, 2017 - Springer
The main route of administration for drug products is the oral route, yet biologics are initially
developed as injectables due to their limited stability through the gastrointestinal tract and …

Metronidazole/Hydroxypropyl-β-Cyclodextrin inclusion complex nanofibrous webs as fast-dissolving oral drug delivery system

A Celebioglu, T Uyar - International Journal of Pharmaceutics, 2019 - Elsevier
Abstract In this study, Metronidazole/Hydroxypropyl-β-Cyclodextrin (HP-β-CyD) inclusion
complex nanofibrous webs were produced via electrospinning for the purpose of fast …

Hydrocortisone/cyclodextrin complex electrospun nanofibers for a fast-dissolving oral drug delivery system

A Celebioglu, T Uyar - RSC Medicinal Chemistry, 2020 - pubs.rsc.org
The electrospinning of hydrocortisone/cyclodextrin complex nanofibers was performed in
order to develop a fast-dissolving oral drug delivery system. Hydrocortisone is a water …

[HTML][HTML] Advances in formulation and manufacturing strategies for the delivery of therapeutic proteins and peptides in orally disintegrating dosage forms

S Bashir, R Fitaihi, HE Abdelhakim - European Journal of Pharmaceutical …, 2023 - Elsevier
Therapeutic proteins and peptides (TPPs) are increasingly favoured above small drug
molecules due to their high specificity to the site of action and reduced adverse effects …