This manuscript represents a review of lymphoblastic leukemia/lymphoma (acute
lymphoblastic leukemia/lymphoblastic lymphoma), acute leukemias of ambiguous lineage …

Non-Hodgkin lymphomas develop from nodal and extranodal lymphoid tissues. A distinct
subset of extranodal lymphomas arising from B cells of the marginal zone (MZ) of mucosa …

This is the third volume in the new World Health Organization series on histological and
genetic typing of tumours. Tumours of the haematopoietic and lymphoid tissues are covered …

Ag encounter will recruit Ag-specific cells from the pool of mature B lymphocytes in the
spleen and activate them to perform effector functions: generation of Ab-forming cells …

Summary In the World Health Organization classification system, splenic marginal-zone
lymphoma (splenic MZL) is described as an indolent B-cell lymphoma, which generally …

Splenic marginal zone lymphoma (SMZL) is a specific low-grade small B-cell lymphoma that
is incorporated in the World Health Organization classification. Characteristic features are …

This study aimed to correlate the frequency of somatic mutations in the IgVH gene and the
use of specific segments in the VH repertoire with the clinical and characteristic features of a …

We performed an immunogenetic analysis of 345 IGHV–IGHD–IGHJ rearrangements from
337 cases with primary splenic small B-cell lymphomas of marginal-zone origin. Three …

Antigen stimulation may be important for splenic marginal zone lymphoma pathogenesis. To
address this hypothesis, the occurrence of stereotyped B-cell receptors was investigated in …

Marginal-zone B cells are likely to be the first B cells in lymphoid tissue to encounter antigen.
Here, Jo Spencer and colleagues review their distribution, properties and malignancies, and …