A review of recent advances in the modeling of nanoparticle radiosensitization with the Geant4-DNA toolkit

A Taheri, MU Khandaker, F Moradi… - Radiation Physics and …, 2023 - Elsevier
Metallic nanoparticles are promising agents for increasing the effectiveness of radiation
therapy by making cells more sensitive to radiation. High atomic number nanoparticles …

[HTML][HTML] Theranostics and artificial intelligence: new frontiers in personalized medicine

GB Bilgin, C Bilgin, BJ Burkett, JJ Orme, DS Childs… - Theranostics, 2024 - ncbi.nlm.nih.gov
The field of theranostics is rapidly advancing, driven by the goals of enhancing patient care.
Recent breakthroughs in artificial intelligence (AI) and its innovative theranostic applications …

A radiomic‐ and dosiomic‐based machine learning regression model for pretreatment planning in 177Lu‐DOTATATE therapy

D Plachouris, V Eleftheriadis, T Nanos… - Medical …, 2023 - Wiley Online Library
Background Standardized patient‐specific pretreatment dosimetry planning is mandatory in
the modern era of nuclear molecular radiotherapy, which may eventually lead to …

Optimization of Y-90 radioembolization imaging for Post-treatment Dosimetry on a long Axial Field-of-view PET/CT scanner

PM Linder, W Lan, NF Trautwein, J Brosch-Lenz… - Diagnostics, 2023 - mdpi.com
Background: PET imaging after yttrium-90 (Y-90) radioembolization is challenging because
of the low positron fraction of Y-90 (32× 10− 6). The resulting low number of events can be …

Optical Photon Propagation Characteristics and Thickness Optimization of LaCl3:Ce and LaBr3:Ce Crystal Scintillators for Nuclear Medicine Imaging

S Tseremoglou, C Michail, I Valais, K Ninos, A Bakas… - Crystals, 2023 - mdpi.com
The present study focuses on the determination of the optimal crystal thickness of LaCl3: Ce
and LaBr3: Ce crystal scintillators for Nuclear Medicine Imaging applications. A theoretical …

Annihilation photon GAN source model for PET Monte Carlo simulation

D Sarrut, A Etxebeste, T Kaprelian… - Physics in Medicine …, 2023 - iopscience.iop.org
Objective. Following previous works on virtual sources model with Generative Adversarial
Network (GAN), we extend the proof of concept for generating back-to-back pairs of gammas …

A framework for prediction of personalized pediatric nuclear medical dosimetry based on machine learning and Monte Carlo techniques

V Eleftheriadis, G Savvidis, V Paneta… - Physics in Medicine …, 2023 - iopscience.iop.org
Objective: A methodology is introduced for the development of an internal dosimetry
prediction toolkit for nuclear medical pediatric applications. The proposed study exploits …

Monte Carlo simulations of microdosimetry and radiolytic species production at long time post proton irradiation using GATE and Geant4‐DNA

GR Fois, HN Tran, V Fiegel, G Blain… - Medical …, 2024 - Wiley Online Library
Background Radiobiological effectiveness of radiation in cancer treatment can be studied at
different scales (molecular till organ scale) and different time post irradiation. The production …

A generative adversarial network to speed up optical Monte Carlo simulations

C Trigila, A Srikanth, E Roncali - Machine Learning: Science and …, 2023 - iopscience.iop.org
Detailed simulation of optical photon transport and detection in radiation detectors is often
used for crystal-based gamma detector optimization. However, the time and memory burden …

Multi-layered structures for lightweight providing shielding from unintended radiation exposure for pediatric patients

DE Kwon, DH Han, JO Kim, KH Jung… - Radiation Physics and …, 2023 - Elsevier
The field of medical radiation shielding aims to minimize unnecessary radiation exposure.
However, lead-based materials have significant drawbacks including toxicity, heavy weight …