Synergetic dual antibiotics-loaded chitosan/poly (vinyl alcohol) nanofibers with sustained antibacterial delivery for treatment of XDR bacteria-infected wounds

S Alizadeh, P Farshi, N Farahmandian… - International Journal of …, 2023 - Elsevier
Resistance of bacterial pathogens to conventional antibiotics has remained a significant
challenge in managing post-wound infections, especially in developing countries. Here, a …

[HTML][HTML] Antimicrobial and antibiofilm potentiation by a triple combination of dual biocides and a phytochemical with complementary activity

S Fernandes, IB Gomes, M Simões - Food Research International, 2023 - Elsevier
The failure of current sanitation practices requires the development of effective solutions for
microbial control. Although combinations using antibiotics have been extensively studied to …

Geographic patterns of carbapenem-resistant, multi-drug-resistant and difficult-to-treat Acinetobacter baumannii in the Asia-Pacific region: results from the …

CH Chen, PH Wu, MC Lu, MW Ho, PR Hsueh - International Journal of …, 2023 - Elsevier
This study evaluated the in-vitro activity of multiple classes of antibiotics, including novel β-
lactam combination agents, tigecycline and colistin, against carbapenem-resistant (CRAB) …

Exploring Synergistic Combinations in Extended and Pan-Drug Resistant (XDR and PDR) Whole Genome Sequenced Acinetobacter baumannii

MAL Quraini, ZAL Jabri, H Sami, J Mahindroo… - Microorganisms, 2023 - mdpi.com
Background: The diminishing antimicrobial options for the treatment of XDR and PDR
Acinetobacter baumannii is an increasing concern. In this study, we assessed the in vitro …

[HTML][HTML] Prevalence and Phenotypic and Molecular Characterization of Carbapenemase-Producing Gram-Negative Bacteria in Gabon

AC Dikoumba, R Onanga, H Jean-Pierre… - The American Journal …, 2023 - ncbi.nlm.nih.gov
Data collection and monitoring of carbapenemase-producing (CP) Gram-negative bacteria
(GNB) are often limited. This study determined CP-GNB prevalence in Gabon and the …

Rifampicin Enhanced Carbapenem Activity with Improved Antibacterial Effects and Eradicates Established Acinetobacter baumannii Biofilms

LC Nwabor, A Chukamnerd, OF Nwabor, R Pomwised… - Pharmaceuticals, 2023 - mdpi.com
Biofilm-mediated infections are critical to public health and a leading cause of resistance
among pathogens, amounting to a prolonged hospital stay and increased mortality rate in …

Propranolol restores susceptibility of XDR Gram-negative pathogens to meropenem and Meropenem combination has been evaluated with either tigecycline or …

SS Mabrouk, GR Abdellatif, ASA Zaid, KM Aboshanab - BMC microbiology, 2023 - Springer
Background Infection with extensive-drug-resistant (XDR) carbapenem-resistant (CR) Gram-
negative bacteria (GNB) are viewed as a serious threat to human health because of the …

Synergistic Effects of a Probiotic Culture Extract and Antimicrobial Combinations against Multidrug-Resistant Acinetobacter baumannii

JH Lee, J Kim, GY Kim - Medicina, 2023 - mdpi.com
Background and Objectives: Developing effective treatment outcomes for multidrug-resistant
Acinetobacter baumannii (MRAB) infections, with colistin and tigecycline the current frontline …

Genotypic and phenotypic mechanisms underlying antimicrobial resistance and synergistic efficacy of rifampicin-based combinations against carbapenem-resistant …

LC Nwabor, A Chukamnerd, OF Nwabor, K Surachat… - Heliyon, 2024 - cell.com
Abstract Purpose Carbapenem-resistant Acinetobacter baumannii (CRAB) is an urgent
concern to public health. This study focuses on exploring the resistance mechanisms and …

Antimicrobial combination effects against multidrug‐resistant Acinetobacter baumannii and Pseudomonas aeruginosa strains: A cross‐sectional study

H Kazemian, M Karami‐Zarandi, H Heidari… - Health Science …, 2024 - Wiley Online Library
Abstract Background and Aims Emergence of multidrug resistance in non‐fermenting Gram‐
negative bacilli is a threat to public health. Combination therapy is a strategy for the …