In humans, the thyroid hormones T3 and T4 are synthesized in the thyroid gland in a
process that crucially involves the iodoglycoprotein thyroglobulin. The overall structure of …

Obesity and thyroid diseases are common disorders in the general population and they
frequently occur in single individuals. Alongside a chance association, a direct relationship …

Subclinical hypothyroidism (SCH) should be considered in two categories according to the
elevation in serum thyroid-stimulating hormone (TSH) level: mildly increased TSH levels (4.0 …

Thyroid stimulating hormone (TSH) is critical for normal development and metabolism. To
better understand the genetic contribution to TSH levels, we conduct a GWAS meta-analysis …

Context: TSH is the major growth factor for thyrocytes and may have a causative role in
thyroid cancer. Objective: The objective of the study was to systematically assess the …

In the last two decades thyroid cancer incidence has increased worldwide more than any
other cancer. Overdiagnosis of subclinical microcarcinomas has certainly contributed to this …

Background. Hashimoto's thyroiditis (HT) and higher levels of thyroid‐stimulating hormone
(TSH) have been proposed as risk factors for papillary thyroid cancer (PTC), but this issue is …

Purpose Congenital primary hypothyroidism (CH) is a state of inadequate thyroid hormone
production detected at birth, caused either by absent, underdeveloped or ectopic thyroid …

Subclinical hypothyroidism (SCH) is defined as elevated thyroid stimulating hormone (TSH)
with normal levels of free triiodothyronine (FT3) and free thyroxine (FT4). SCH is further …

Pollutants represent potential threats to the human health, being ubiquitous in the
environment and exerting toxicity even at low doses. This study aims at investigating the role …