Thermally active TRPV1 tonically drives central spontaneous glutamate release

K Shoudai, JH Peters, SJ McDougall… - Journal of …, 2010 - Soc Neuroscience
Central synapses spontaneously release neurotransmitter at low rates. In the brainstem,
cranial visceral afferent terminals in caudal solitary tract nucleus (NTS) display pronounced …

Organization and properties of GABAergic neurons in solitary tract nucleus (NTS)

TW Bailey, SM Appleyard, YH Jin… - Journal of …, 2008 - journals.physiology.org
Cranial visceral afferents enter the brain at the solitary tract nucleus (NTS). GABAergic
neurons are scattered throughout the NTS, but their relation to solitary tract (ST) afferent …

Leptin sensitizes NTS neurons to vagal input by increasing postsynaptic NMDA receptor currents

D Neyens, H Zhao, NJ Huston… - Journal of …, 2020 - Soc Neuroscience
Leptin signaling within the nucleus of the solitary tract (NTS) contributes to the control of food
intake, and injections of leptin into the NTS reduce meal size and increase the efficacy of …

Perampanel Inhibits α‐Synuclein Transmission in Parkinson's Disease Models

J Ueda, N Uemura, M Sawamura, T Taguchi… - Movement …, 2021 - Wiley Online Library
Background The intercellular transmission of pathogenic proteins plays a key role in the
clinicopathological progression of neurodegenerative diseases. Previous studies have …

Vagus nerve stimulation activates nucleus of solitary tract neurons via supramedullary pathways

CM Cooper, AQ Farrand, MC Andresen… - The Journal of …, 2021 - Wiley Online Library
Vagus nerve stimulation (VNS) treats patients with drug‐resistant epilepsy, depression and
heart failure, but the mechanisms responsible are uncertain. The mild stimulus intensities …

Circadian regulation of glutamate release pathways shapes synaptic throughput in the brainstem nucleus of the solitary tract (NTS)

FJ Ragozzino, BA Peterson… - The Journal of …, 2023 - Wiley Online Library
Circadian regulation of autonomic reflex pathways pairs physiological function with the daily
light cycle. The brainstem nucleus of the solitary tract (NTS) is a key candidate for rhythmic …

Sparse genetic tracing reveals regionally specific functional organization of mammalian nociceptors

W Olson, I Abdus-Saboor, L Cui, J Burdge, T Raabe… - elife, 2017 - elifesciences.org
The human distal limbs have a high spatial acuity for noxious stimuli but a low density of
pain-sensing neurites. To elucidate mechanisms underlying regional differences in …

Auditory thalamocortical transmission is reliable and temporally precise

HJ Rose, R Metherate - Journal of neurophysiology, 2005 - journals.physiology.org
We have used the auditory thalamocortical slice to characterize thalamocortical transmission
in primary auditory cortex (ACx) of the juvenile mouse.“Minimal” stimulation was used to …

Vasopressin inhibits glutamate release via two distinct modes in the brainstem

TW Bailey, YH Jin, MW Doyle, SM Smith… - Journal of …, 2006 - Soc Neuroscience
The hypothalamus coordinates autonomic responses in part through arginine vasopressin
(AVP) released in medial nucleus tractus solitarius (NTS). However, the mechanisms and …

Activity regulates the incidence of heteronymous sensory-motor connections

AI Mendelsohn, CM Simon, LF Abbott, GZ Mentis… - Neuron, 2015 - cell.com
The construction of spinal sensory-motor circuits involves the selection of appropriate
synaptic partners and the allocation of precise synaptic input densities. Many aspects of …