Active targeting can improve the retention of drugs and drug delivery systems in tumors,
thereby enhancing their therapeutic efficacy. In this context, vitamin receptors that are …

Inborn errors of Riboflavin (Rf) transport and metabolism have been recently related to
severe human neuromuscular disorders, as resulting in profound alteration of human …

Abstract Background Hypoxia-inducible factors (HIFs) are the most essential endogenous
transcription factors in the hypoxic microenvironment and regulate multiple genes involved …

Riboflavin transporter deficiency (RTD) is a childhood‐onset neurodegenerative disorder
characterized by progressive pontobulbar palsy, sensory and motor neuron degeneration …

Riboflavin (vitamin B2) is essential for cellular growth and function. It is enzymatically
converted to flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD), which …

Ascorbic acid (AA) uptake in neurons occurs via a Na+-dependent carrier-mediated process
mediated by the sodium-dependent vitamin C transporter-2 (SVCT2). Relatively little …

The human sodium-dependent vitamin C transporter-1 (hSVCT1) is localized at the apical
membrane domain of polarized intestinal and renal epithelial cells to mediate ascorbic acid …

Riboflavin (RF, vitamin B2) plays a key role in metabolic oxidation–reduction reactions,
especially in the mitochondrial reprogramming of energy metabolism. Riboflavin transporter …

Cancer remains the number one cause of death worldwide (Bray et al. 2021). In 2020 almost
10 million people died due to cancer (Sung et al. 2021). Current treatment options include …

Ascorbic acid (AA) uptake in neurons occurs via a Na+-dependent carrier-mediated process
mediated by the sodium-dependent vitamin C transporter-2 (SVCT2). Relatively little …