Musculoskeletal soft tissue injuries are very common and usually occur during both sporting
and everyday activities. The intervention of adjuvant therapies to promote tissue …

Osteoarthritis (OA) represents an enduring and widespread global burden, causing
significant morbidity and disability, whose pathology is characterized by persistent …

Osteoarthritis, a chronic degenerative cartilage disease, is the leading cause of movement
disorders among humans. Although the specific pathogenesis and associated mechanisms …

Background: Low-intensity pulsed ultrasound (LIPUS, a form of mechanical stimulation) can
promote skeletal muscle functional repair, but a lack of mechanistic understanding of its …

Objective: Synovitis and fibrosis are common pathological features of knee osteoarthritis
(KOA). The interaction of synovitis and fibrosis can promote KOA progression. Chrysin …

CTGF is a multifunctional protein and plays different roles in different cells and under
different conditions. Pamrevlumab, a monoclonal antibody against CTGF, is an FDA …

Osteoarthritis (OA) is the most common chronic degenerative joint disease in middle‐aged
and elderly people, characterized by joint pain and dysfunction. Macrophages are key …

Background Osteoarthritis (OA) is a degenerative joint disease with lacking effective
prevention targets. A disintegrin and metalloproteinase with thrombospondin motifs 12 …

Osteoarthritis (OA) is the most prevalent disorder of synovial joint affecting multiple joints. In
the past decade, we have witnessed conceptual switch of OA pathogenesis from a 'wear and …

All cells possess an innate ability to respond to a range of mechanical stimuli through their
complex internal machinery. This comprises various mechanosensory elements that detect …