Mesenchymal stem/stromal cell-based therapy: mechanism, systemic safety and biodistribution for precision clinical applications

WZ Zhuang, YH Lin, LJ Su, MS Wu, HY Jeng… - Journal of biomedical …, 2021 - Springer
Mesenchymal stem/stromal cells (MSCs) are a promising resource for cell-based therapy
because of their high immunomodulation ability, tropism towards inflamed and injured …

Pathogenesis of endometriosis: the origin of pain and subfertility

TM Gruber, S Mechsner - Cells, 2021 - mdpi.com
Endometriosis (EM) and adenomyosis (AM) are common conditions with pain and infertility
as the principal symptoms. The pathophysiology of pain in EM and AM comprises sensory …

Recurrent implantation failure: A comprehensive summary from etiology to treatment

J Ma, W Gao, D Li - Frontiers in Endocrinology, 2023 - frontiersin.org
Implantation is the first step in human reproduction. Successful implantation depends on the
crosstalk between embryo and endometrium. Recurrent implantation failure (RIF) is a …

Endometriosis associated infertility: a critical review and analysis on etiopathogenesis and therapeutic approaches

L Filip, F Duică, A Prădatu, D Crețoiu, N Suciu… - Medicina, 2020 - mdpi.com
Endometriosis represents a frequently diagnosed gynecological affliction in the reproductive
timespan of women, defined by symptoms ranging from pelvic pain to infertility. A complex …

Impaired inflammatory state of the endometrium: a multifaceted approach to endometrial inflammation. Current insights and future directions

A Drizi, D Djokovic, AS Laganà… - Menopause Review …, 2020 - termedia.pl
Methods A non-systematic review was done through a search on the following databases:
MEDLINE, EMBASE, Global Health, The Cochrane Library (Cochrane Database of …

Role of AMPK/mTOR, mitochondria, and ROS in the pathogenesis of endometriosis

L Assaf, AA Eid, J Nassif - Life sciences, 2022 - Elsevier
Endometriosis is the presence of endometrial tissue outside the uterine cavity usually in the
ovaries, fallopian tube, and pelvic cavity. It's a chronic enigmatic gynecological condition …

The role of iron in the pathogenesis of endometriosis: a systematic review

J Wyatt, SM Fernando, SG Powell, CJ Hill… - Human …, 2023 - academic.oup.com
STUDY QUESTION What is the role of iron in the pathophysiology of endometriosis?
SUMMARY ANSWER Iron excess is demonstrated wherever endometriotic tissues are found …

Role of inflammation in benign gynecologic disorders: from pathogenesis to novel therapies

A AlAshqar, L Reschke, GW Kirschen… - Biology of …, 2021 - academic.oup.com
Emerging evidence supports the notion that inflammation fosters the development of
common benign gynecologic disorders, including uterine leiomyoma, endometriosis, and …

Endometriosis treatment: role of natural polyphenols as anti-inflammatory agents

V Tassinari, A Smeriglio, V Stillittano, D Trombetta… - Nutrients, 2023 - mdpi.com
Endometriosis is an estrogen-dependent common chronic inflammatory disease defined by
the presence of extrauterine endometrial tissue that promotes pelvic pain and fertility …

Correlation of fecal metabolomics and gut microbiota in mice with endometriosis

Z Ni, S Sun, Y Bi, J Ding, W Cheng, J Yu… - American Journal of …, 2020 - Wiley Online Library
Problem Endometriosis (EMS) is a chronic inflammatory disease with unclear pathogenesis.
Three studies have uncovered the influence of gut microbiota on mice with EMS, but no …