The diversity of conjugative relaxases and its application in plasmid classification
MP Garcillán-Barcia, MV Francia… - FEMS microbiology …, 2009 - academic.oup.com
Bacterial conjugation is an efficient and sophisticated mechanism of DNA transfer among
bacteria. While mobilizable plasmids only encode a minimal MOB machinery that allows …
bacteria. While mobilizable plasmids only encode a minimal MOB machinery that allows …
From conjugation to T4S systems in Gram‐negative bacteria: a mechanistic biology perspective
G Waksman - EMBO reports, 2019 - embopress.org
Conjugation is the process by which bacteria exchange genetic materials in a unidirectional
manner from a donor cell to a recipient cell. The discovery of conjugation signalled the dawn …
manner from a donor cell to a recipient cell. The discovery of conjugation signalled the dawn …
Conjugative DNA metabolism in Gram-negative bacteria
F De La Cruz, LS Frost, RJ Meyer… - FEMS microbiology …, 2010 - academic.oup.com
Bacterial conjugation in Gram-negative bacteria is triggered by a signal that connects the
relaxosome to the coupling protein (T4CP) and transferosome, a type IV secretion system …
relaxosome to the coupling protein (T4CP) and transferosome, a type IV secretion system …
Bacterial conjugation: a two‐step mechanism for DNA transport
M Llosa, FX Gomis‐Rüth, M Coll… - Molecular …, 2002 - Wiley Online Library
Bacterial conjugation is a promiscuous DNA transport mechanism. Conjugative plasmids
transfer themselves between most bacteria, thus being one of the main causal agents of the …
transfer themselves between most bacteria, thus being one of the main causal agents of the …
MOBscan: automated annotation of MOB relaxases
MP Garcillán-Barcia, S Redondo-Salvo… - Horizontal gene transfer …, 2020 - Springer
Relaxase-based plasmid classification has become popular in the past 10 years.
Nevertheless, it is not obvious how to assign a query protein to a relaxase MOB family …
Nevertheless, it is not obvious how to assign a query protein to a relaxase MOB family …
[HTML][HTML] The expanding bacterial type IV secretion lexicon
M Bhatty, JAL Gomez, PJ Christie - Research in microbiology, 2013 - Elsevier
The bacterial type IV secretion systems (T4SSs) comprise a biologically diverse group of
translocation systems functioning to deliver DNA or protein substrates from donor to target …
translocation systems functioning to deliver DNA or protein substrates from donor to target …
The mating pair formation system of conjugative plasmids—a versatile secretion machinery for transfer of proteins and DNA
G Schröder, E Lanka - Plasmid, 2005 - Elsevier
The mating pair formation (Mpf) system functions as a secretion machinery for intercellular
DNA transfer during bacterial conjugation. The components of the Mpf system, comprising a …
DNA transfer during bacterial conjugation. The components of the Mpf system, comprising a …
Replication and conjugative mobilization of broad host-range IncQ plasmids
R Meyer - Plasmid, 2009 - Elsevier
The IncQ plasmids have a broader host-range than any other known replicating element in
bacteria. Studies on the replication and conjugative mobilization of these plasmids, which …
bacteria. Studies on the replication and conjugative mobilization of these plasmids, which …
Dynamics of the IncW genetic backbone imply general trends in conjugative plasmid evolution
R Fernández-López, MP Garcillán-Barcia… - FEMS microbiology …, 2006 - academic.oup.com
Plasmids cannot be understood as mere tools for genetic exchange: they are themselves
subject to the forces of evolution. Their genomic and phylogenetic features have been less …
subject to the forces of evolution. Their genomic and phylogenetic features have been less …
Recognition and processing of the origin of transfer DNA by conjugative relaxase TrwC
A Guasch, M Lucas, G Moncalián, M Cabezas… - Nature Structural & …, 2003 - nature.com
Relaxases are DNA strand transferases that catalyze the initial and final stages of DNA
processing during conjugative cell-to-cell DNA transfer. Upon binding to the origin of transfer …
processing during conjugative cell-to-cell DNA transfer. Upon binding to the origin of transfer …