The aryl hydrocarbon receptor (AHR) signaling pathway is a complex regulatory network
that plays a critical role in various biological processes, including cellular metabolism …

Aryl hydrocarbon receptor (AHR) is a ligand-dependent transcription factor. 2, 3, 7, 8-
tetrachlorodibenzo-p-dioxin (TCDD) is a classical exogenous synthetic ligand of AHR that …

Melatonin is widely present in Nature. It has pleiotropic activities, in part mediated by
interactions with high-affinity G-protein-coupled melatonin type 1 and 2 (MT1 and MT2) …

To achieve longevity, IgA plasma cells require a sophisticated anatomical microenvironment
that provides cytokines, cell-cell contacts, and nutrients as well as metabolites. The intestinal …

The aryl hydrocarbon receptor (AhR) is a transcript factor, belonging to the basic helix-loop-
helix-Per-ARNT-SIM family, is closely associated with health and diseases. Targeting AhR is …

Alternaria alternata is a common fungus strongly related with severe allergic asthma, with
80% of affected individuals being sensitized solely to its major allergen Alt a 1. Here, we …

The aryl hydrocarbon receptor (AhR) is a crucial cytosolic evolutionary conserved ligand-
activated transcription factor and a pleiotropic signal transducer. The biosensor activity of the …

Respiratory viral infections are one of the major causes of illness and death worldwide.
Symptoms associated with respiratory infections can range from mild to severe, and there is …

Purpose Uremic cardiomyopathy (UCM) is the leading cause of chronic kidney disease
(CKD) related mortality. Uremic toxins including indoxyl sulfate (IS) play important role …

Bet v 1 is the major allergen in birch pollen to which up to 95% of patients sensitized to birch
respond. As a member of the pathogenesis-related PR 10 family, its natural function is …