Epigenetic alternations concern heritable yet reversible changes in histone or DNA
modifications that regulate gene activity beyond the underlying sequence. Epigenetic …

The combination of an increasing number of new cancer cases and improving survival rates
has led to a large and rapidly growing population with unique health-care requirements …

For a long time, scientists have tried to describe disorders just by genetic or environmental
factors. However, the role of epigenetics in human diseases has been considered from a …

There is increasing interest in applying a precision medicine approach to understanding
exercise as a potential treatment for cancer. We aimed to inform this new approach by …

Breast cancer is an increasing public health problem. Substantial advances have been
made in the treatment of breast cancer, but the introduction of methods to predict women at …

Epigenetic modification refers to heritable changes in gene function that cannot be
explained by alterations in the DNA sequence. The current literature clearly demonstrates …

Background Epigenetics is the study of processes—beyond DNA sequence alteration—
producing heritable characteristics. For example, DNA methylation modifies gene …

The response to exercise training (trainability) has been shown to have a strong heritable
component. There is growing evidence suggesting that traits such as trainability do not only …

Physical activity plays an important role in improving and maintaining the health and well-
being of the cancer survivor. However, the physical and psychological impact of the cancer …

Physical activity is a strong stimulus influencing the overall physiology of the human body.
Exercises lead to biochemical changes in various tissues and exert an impact on gene …