The discovery of kisspeptin as a critical central regulatory factor of GnRH release has given
people a novel understanding of the neuroendocrine regulation in human reproduction …

Endocrine-disrupting chemicals (EDCs) have significant impacts on biological systems, and
have been shown to interfere with physiological systems, especially by disrupting the …

The etiology of central precocious puberty (CPP) is multiple and heterogeneous, including
congenital and acquired causes that can be associated with structural or functional brain …

Endocrine-disrupting chemicals (EDCs) are ubiquitous in daily life, but their harmful effects
on the human body have not been fully explored. Recent studies have shown that EDCs …

Sexual maturation in humans is characterized by a unique individual variability. Pubertal
onset is a highly heritable polygenic trait but it is also affected by environmental factors such …

Background: The effects of endocrine-disrupting chemicals (EDCs) on fertility and
reproductive development represent a rising concern in modern societies. Although the …

Neurons that produce gonadotropin-releasing hormone (GnRH), which control fertility,
complete their nose-to-brain migration by birth. However, their function depends on …

There is evidence in humans that endocrine disrupting chemicals exposure, such as
bisphenol A (BPA), is tied to social behavior impacts when evaluated in early life stage …

The central nervous system (CNS) is a sensitive target for endocrine-disrupting chemicals,
such as bisphenol analogues. Bisphenol A (BPA) usage is associated with the occurrence of …

The pubertal development onset is controlled by a network of genes that regulate the
gonadotropin releasing hormone (GnRH) pulsatile release and the subsequent increase of …