Sarcopenia, sarcopenic obesity and nonalcoholic fatty liver disease

SA Polyzos, ID Vachliotis, CS Mantzoros - Metabolism, 2023 - Elsevier
Nonalcoholic fatty liver disease (NAFLD), sarcopenia and sarcopenic obesity (SO) are
highly prevalent conditions that may coexist, especially in the aging population, without any …

Effect of sodium-glucose transporter 2 inhibitors on sarcopenia in patients with type 2 diabetes mellitus: A systematic review and meta-analysis

S Zhang, Z Qi, Y Wang, D Song, D Zhu - Frontiers in Endocrinology, 2023 - frontiersin.org
Objective Sarcopenia has been recognized as the third category of disabling complications
in patients with type 2 diabetes mellitus (T2DM), in addition to micro-and macrovascular …

Efficacy and safety of the sodium‐glucose co‐transporter‐2 inhibitor empagliflozin in elderly Japanese adults (≥ 65 years) with type 2 diabetes: A randomized, double …

D Yabe, K Shiki, G Homma, T Meinicke… - Diabetes, Obesity …, 2023 - Wiley Online Library
Aim Use of sodium‐glucose co‐transporter‐2 inhibitors (SGLT2is) for glycaemic control is
increasing in individuals with type 2 diabetes (T2D) for their additional benefits on heart …

Low muscle mass is associated with poorer glycemic control and higher oxidative stress in older patients with type 2 diabetes

B Alabadi, M Civera, A De la Rosa, S Martinez-Hervas… - Nutrients, 2023 - mdpi.com
Body composition changes that occur during aging, such as loss of lean mass, are
unfavorable at metabolic level and they can explain, in part, the appearance of certain age …

Sarcopenia and diabetes: A detrimental liaison of advancing age

G Lisco, OE Disoteo, A De Tullio, V De Geronimo… - Nutrients, 2023 - mdpi.com
Sarcopenia is an age-related clinical complaint characterized by the progressive
deterioration of skeletal muscle mass and strength over time. Type 2 diabetes (T2D) is …

Age is just a number: progress and obstacles in the discovery of new candidate drugs for sarcopenia

HJ Kim, DW Jung, DR Williams - Cells, 2023 - mdpi.com
Sarcopenia is a disease characterized by the progressive loss of skeletal muscle mass and
function that occurs with aging. The progression of sarcopenia is correlated with the onset of …

Recent advances in the treatment of patients with obesity and chronic kidney disease

R Abdul Wahab, RV Cohen, CW le Roux - Annals of Medicine, 2023 - Taylor & Francis
Obesity is a chronic disease characterised by excess adiposity, which impairs health. The
high prevalence of obesity raises the risk of long-term medical complications including type …

Pathophysiological interactions between sarcopenia and type 2 diabetes: A two‐way street influencing diagnosis and therapeutic options

W Tack, AM De Cock, EL Dirinck… - Diabetes, Obesity …, 2024 - Wiley Online Library
This review will try to elucidate the interconnected pathophysiology of sarcopenia and type 2
diabetes (T2D) and will try to identify a common pathway to explain their development. To …

[HTML][HTML] SGLT2-inhibition increases total, LDL, and HDL cholesterol and lowers triglycerides: Meta-analyses of 60 randomized trials, overall and by dose, ethnicity …

LE Bechmann, F Emanuelsson, BG Nordestgaard… - Atherosclerosis, 2024 - Elsevier
Background and aims Sodium glucose co-transporter 2 (SGLT2)-inhibitors were developed
as glucose-lowering drugs. Surprisingly, SGLT2-inhibitors also reduced risk of …

Efficacy and safety of the use of SGLT2 inhibitors in patients on incremental hemodialysis: maximizing residual renal function, is there a role for SGLT2 inhibitors?

JC De La Flor, D Villa, L Cruzado, J Apaza, F Valga… - Biomedicines, 2023 - mdpi.com
SGLT-2i are the new standard of care for diabetic kidney disease (DKD), but previous
studies have not included patients on kidney replacement therapy (KRT). Due to their high …