Zinc is involved in a variety of biological processes, as a structural, catalytic, and intracellular
and intercellular signaling component. Thus zinc homeostasis is tightly controlled at the …

Zinc (Zn) is an essential trace mineral that regulates the expression and activation of
biological molecules such as transcription factors, enzymes, adapters, channels, and growth …

Zinc metabolism at the cellular level is critical for many biological processes in the body. A
key observation is the disruption of cellular homeostasis, often coinciding with disease …

The actions of androgens such as testosterone and dihydrotestosterone are mediated via
the androgen receptor (AR), a ligand-dependent nuclear transcription factor and member of …

Pulmonary hypertension (PH) encompasses a syndrome of diseases that are characterized
by elevated pulmonary artery pressure and pulmonary vascular remodeling and that …

The role of androgen receptor (AR) activation and expression is well understood in prostate
cancer. In breast cancer, expression and activation of AR is increasingly recognized for its …

Zinc is a critical component in a number of conserved processes that regulate female germ
cell growth, fertility, and pregnancy. During follicle development, a sufficient intracellular …

Prostate cancer (PC), which has high morbidity and mortality among elderly men, is
becoming the most common malignancy in men. The progression of PC is associated with …

The principle steroidal androgens are testosterone and its metabolite 5α-
dihydrotestosterone (DHT), which is converted from testosterone by the enzyme 5α …

The Zrt‐/Irt‐like protein (ZIP) family consists of divalent metal transporters, ubiquitous in all
kingdoms of life. Since the discovery of the first ZIPs in the 1990s, the ZIP family has been …