The response of prostate smooth muscle cells to testosterone is determined by the subcellular distribution of the androgen receptor

N Peinetti, MV Scalerandi, MM Cuello Rubio… - …, 2018 - academic.oup.com
Androgen signaling in prostate smooth muscle cells (pSMCs) is critical for the maintenance
of prostate homeostasis, the alterations of which are a central aspect in the development of …

Growth increase and gonadal dysfunction of the lined seahorse triggered by zinc exposure

X Han, C Li, G Qin, X Wang, B Zhang, Q Lin - Aquatic Toxicology, 2024 - Elsevier
Seahorses are characterized by unique characteristics such as a male pregnancy
reproductive strategy and grasping preferences, which make these species vulnerable to …

[HTML][HTML] Testosterone/bicalutamide antagonism at the predicted extracellular androgen binding site of ZIP9

A Bulldan, VN Malviya, N Upmanyu, L Konrad… - … et Biophysica Acta (BBA …, 2017 - Elsevier
ZIP9 is a Zn 2+ transporter, testosterone receptor, and mediator of signaling events through
G-proteins. Despite these pivotal properties, however, its physiological and …

ZnT8 haploinsufficiency impacts MIN6 cell zinc content and β-cell phenotype via ZIP-ZnT8 coregulation

R Lawson, W Maret, C Hogstrand - International journal of molecular …, 2019 - mdpi.com
The zinc transporter ZnT8 (SLC30A8) localises to insulin secretory granules of β-cells where
it facilitates zinc uptake for insulin crystallisation. ZnT8 abundance has been linked to β-cell …

The role of ZIP9 and androgen receptor in the establishment of tight junctions between adult rat sertoli cells

H Kabbesh, A Bulldan, L Konrad, G Scheiner-Bobis - Biology, 2022 - mdpi.com
Simple Summary Haploid male germ cells that originate at the onset of puberty from diploid
precursor cells would be attacked by the innate immune system if they were not protected by …

Zinc dyshomeostasis in cardiomyocytes after acute hypoxia/reoxygenation

VL Bodiga, S Thokala, SM Kovur, S Bodiga - Biological trace element …, 2017 - Springer
Zinc dyshomeostasis may play a role in the pathogenesis of myocardial
ischemia/reperfusion injury. The objective of this study was to investigate the expression …

The crossroads between zinc and steroidal implant-induced growth of beef cattle

EM Messersmith, DT Smerchek, SL Hansen - Animals, 2021 - mdpi.com
Simple Summary This review addresses the physiological and biochemical connections
between steroidal implants and Zn and their interaction to influence growth in beef cattle …

[HTML][HTML] Knockdown of zinc transporter ZIP5 by RNA interference inhibits esophageal cancer growth in vivo

Q Li, J Jin, J Liu, L Wang, Y He - Oncology Research, 2016 - ncbi.nlm.nih.gov
We recently found that SLC39A5 (ZIP5), a zinc transporter, is overexpressed in esophageal
cancer. Downregulation of ZIP5 inhibited the proliferation, migration, and invasion of the …

Gender differences in urothelial bladder cancer: effects of natural killer lymphocyte immunity

CT Lutz, L Livas, SR Presnell, M Sexton… - Journal of Clinical …, 2021 - mdpi.com
Men are more likely to develop cancer than women. In fact, male predominance is one of the
most consistent cancer epidemiology findings. Additionally, men have a poorer prognosis …

Anabolic Steroids Activate the NF-κB Pathway in Porcine Ovarian Putative Stem Cells Independently of the ZIP-9 Receptor

K Wartalski, J Wiater, P Maciak, A Pastuła… - International Journal of …, 2024 - mdpi.com
Boldenone (Bdn) and nandrolone (Ndn) are anabolic androgenic steroids (AASs) that, as
our previous studies have shown, may increase the risk of neoplastic transformation of …