Neutrophils are main players in the effector phase of the host defense against micro-
organisms and have a major role in the innate immune response. Neutrophils show …

Neutrophils play a critical role in the host defense against bacterial and fungal infections, but
their inappropriate activation also contributes to tissue damage during autoimmune and …

Sepsis remains a leading cause of death worldwide, despite advances in critical care, and
understanding of the pathophysiology and treatment strategies. No specific therapy or drugs …

Viral respiratory infections are a common cause of severe disease, especially in infants,
people who are immunocompromised, and in the elderly. Neutrophils, an important innate …

Phagocytosis, a critical early event in the microbicidal response of neutrophils, is now
appreciated to serve multiple functions in a variety of cell types. Professional phagocytes …

Pneumonia is the leading infectious cause of mortality worldwide and one of the most
common lower respiratory tract infections that is contributing significantly to the burden of …

The role of polymorphonuclear neutrophils (PMNs) in biology is often recognized during
pathogenesis associated with PMN hyper-or hypo-functionality in various disease states …

Rationale: Although the outcome of sepsis benefits from the prompt administration of
appropriate antibiotics on correct diagnosis, the assessment of infection in critically ill …

Neutrophils (polymorphonuclear cells; PMNs) form a first line of defense against pathogens
and are therefore an important component of the innate immune response. As a result of …

Biomarkers have great potential to improve the diagnosis and treatment of sepsis. The
available literature supports the potential utility of sTREM-1, IL-27, suPAR, neutrophil CD64 …