[PDF][PDF] Recombinant WNTs differentially activate b-catenin-dependent and-independent signalling in mouse microglia-like cells

MB Kilander, C Halleskog, G Schulte - Acta Physiol, 2011 - academia.edu
Aim: The objective of this study was to compare the efficacy of different recombinant,
commercially available Wingless/Int-1 (WNTs) with regard to WNT/b-catenin signalling …

[图书][B] WNT/Frizzled Signaling: Illuminating the Road Towards Pathway Selectivity

CF Bowin - 2021 - search.proquest.com
Cells sense and respond to their environment via receptors embedded in the plasma
membrane. Receptors allow flow of information from outside to the inside of the cell and are …

The molecular code involved in midbrain dopaminergic neuron development and maintenance

C Perrone-Capano, F Volpicelli, U di Porzio - Rendiconti Lincei, 2008 - Springer
Midbrain dopaminergic neurons comprise a small group of cells that regulate important
functions in the mammalian brain. Their degeneration or dysfunction is involved in many …

[HTML][HTML] International Union of Basic and Clinical Pharmacology Review: WNT/Frizzled signalling: receptor–ligand selectivity with focus on FZD-G protein signalling …

JP Dijksterhuis, J Petersen… - British Journal of …, 2014 - ncbi.nlm.nih.gov
Abstract The wingless/int1 (WNT)/Frizzled (FZD) signalling pathway controls numerous
cellular processes such as proliferation, differentiation, cell-fate decisions, migration and …

Molecular manipulation targeting regulation of dopaminergic differentiation and proliferation of neural stem cells or pluripotent stem cells

YX Ding, LC Wei, YZ Wang, R Cao… - CNS & Neurological …, 2011 - ingentaconnect.com
Parkinson's disease (PD) is a severe deliberating neurological disease caused by
progressive degenerative death of dopaminergic neurons in the substantia nigra of …

Roles of Wnt/β-catenin signaling in controlling the dopaminergic neuronal cell commitment of midbrain and therapeutic application for Parkinson's disease

LW Chen - Trends in cell signaling pathways in neuronal fate …, 2013 - books.google.com
Parkinson's disease (PD) is a severe deliberating neurodegenerative disease resulting from
progressive and massive cell death of dopaminergic (DA) neurons in the substantia nigra …

Class Frizzled GPCRs in GtoPdb v. 2023.1

E Arthofer, J Dijksterhuis, L Grätz, B Hot… - IUPHAR/BPS Guide …, 2023 - journals.ed.ac.uk
Abstract Receptors of the Class Frizzled (FZD, nomenclature as agreed by the NC-IUPHAR
subcommittee on the Class Frizzled GPCRs [180]), are GPCRs originally identified in …

[图书][B] Brain regions and cell type specific Wnt signalling changes in Parkinson's disease mouse models

SH Lei - 2023 - search.proquest.com
Parkinson's disease (PD) is a late onset neurodegenerative disease characterised by the
loss of dopaminergic neurons with motor and cognitive symptoms. Different mutations have …

Class Frizzled GPCRs (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database

E Arthofer, J Dijksterhuis, B Hot… - IUPHAR/BPS Guide …, 2019 - journals.ed.ac.uk
Abstract Receptors of the Class Frizzled (FZD, nomenclature as agreed by the NC-IUPHAR
subcommittee on the Class Frizzled GPCRs [156]), are GPCRs originally identified in …

Class Frizzled GPCRs in GtoPdb v. 2021.3

E Arthofer, J Dijksterhuis, B Hot… - IUPHAR/BPS Guide …, 2021 - journals.ed.ac.uk
Abstract Receptors of the Class Frizzled (FZD, nomenclature as agreed by the NC-IUPHAR
subcommittee on the Class Frizzled GPCRs [175]), are GPCRs originally identified in …