[HTML][HTML] Role of NLRP3 in the pathogenesis and treatment of gout arthritis

Y Liu, J Wang, J Li - Frontiers in Immunology, 2023 - frontiersin.org
Gout arthritis (GA) is a common and curable type of inflammatory arthritis that has been
attributed to a combination of genetic, environmental and metabolic factors. Chronic …

[HTML][HTML] Polydatin alleviates hyperuricemia combined with gouty arthritis in mice via regulating urate transporters, NLRP3 inflammasome and NF-κB pathway

W Xu, Y Chen, F Li, X Zhang, C Li, C Wu… - Journal of Functional …, 2023 - Elsevier
Gout is a metabolic disease that seriously affects people's health. Polydatin, a stilbene
compound isolated from Polygonum cuspidatum, has attracted much attention because of its …

[HTML][HTML] Traditional Herbal Medicine: Therapeutic Potential in Acute Gouty Arthritis

S Wang, W Liu, B Wei, A Wang, Y Wang… - Journal of …, 2024 - Elsevier
Abstract Ethnopharmacological relevance Acute Gouty Arthritis (AGA) is characterized by a
rapid inflammatory reaction caused by the build-up of monosodium urate (MSU) crystals in …

Component identification of modified sanmiao pills by UPLC-Xevo G2-XS QTOF and its anti-gouty arthritis mechanism based on network pharmacology and …

R Chen, F Li, K Zhou, M Xing, X Zhang, X Zhao… - Journal of …, 2023 - Elsevier
Ethnopharmacological relevance Modified sanmiao pills (MSMP), a traditional Chinese
medicine (TCM) formula, is consisted of rhizome of Smilax glabra Roxb., Cortexes of …

[HTML][HTML] Neoisoastilbin Ameliorates Acute Gouty Arthritis via Suppression of the NF-κB/NLRP3 Pathway

Y Wang, X Zhang, C Xu, Y Yao, C Wu, W Xu… - Evidence-Based …, 2023 - hindawi.com
Acute gouty arthritis (AGA) is an acute inflammatory disease, whose occurrence and
development mechanism are associated with inflammatory reaction of joint tissue. This study …

Phytoconstituents of Androstachys johnsonii Prain Prevent Reactive Oxygen Species Production and Regulate the Expression of Inflammatory Mediators in LPS …

E Mfotie Njoya, GT Tabakam, CI Chukwuma… - Antioxidants, 2024 - mdpi.com
According to a survey, the medicinal use of Androstachys johnsonii Prain is kept secret by
traditional healers. Considering that inflammation and oxidative stress are major risk factors …

Astilbin inhibited neutrophil extracellular traps in gouty arthritis through suppression of purinergic P2Y6 receptor

C Li, Y Huang, C Wu, Y Qiu, L Zhang, J Xu, J Zheng… - Phytomedicine, 2024 - Elsevier
Background Gouty arthritis (GA), a common inflammatory condition triggered by
monosodium urate crystal accumulation, often necessitates safer treatment alternatives due …

[HTML][HTML] Exploring effect of herbal monomers in treating gouty arthritis based on nuclear factor-kappa B signaling: A review

Z Guo, G Ye, C Tang, H Xiong - Medicine, 2024 - journals.lww.com
Gouty arthritis (GA) is an inflammatory disease caused by disorders of the purine
metabolism. Although increasing number of drugs have been used to treat GA with the …

Kaempferol suppresses inflammation in mice suffering from both hyperuricemia and gouty arthritis through inhibiting NLRP3 inflammasome and NF-κB pathway

Y Huang, C Li, W Xu, F Li, C Xu, C Wu, Y Wang… - 2023 - researchsquare.com
The co-occurrence of hyperuricemia and gouty arthritis is common in patients, yet a suitable
animal model for this condition is lacking. In present study, a mice model combined …

[HTML][HTML] Preventive and Therapeutic Effects of Epicatechin on Acetaminophen-Induced Liver Injury in Mice

F Dehbashi, L Zeidooni, E Mansouri… - Jundishapur Journal of …, 2023 - brieflands.com
Background: Nowadays, the use of over-the-counter drugs such as acetaminophen (APAP)
may cause severe liver injury, which can occur not only in high doses but also in therapeutic …