Ovarian cancer immunotherapy: preclinical models and emerging therapeutics

CW McCloskey, GM Rodriguez, KJC Galpin… - Cancers, 2018 - mdpi.com
Immunotherapy has emerged as one of the most promising approaches for ovarian cancer
treatment. The tumor microenvironment (TME) is a key factor to consider when stimulating …

A review of principal studies on the development and treatment of epithelial ovarian cancer in the laying hen Gallus gallus

P Pal, KN Starkweather, KH Hales… - Comparative …, 2021 - ingentaconnect.com
Often referred to as the silent killer, ovarian cancer is the most lethal gynecologic
malignancy. This disease rarely shows any physical symptoms until late stages and no …

Glucose-regulated protein 78 is a potential serum and imaging marker for early detection of ovarian cancer

EA Paris, JM Bahr, JS Abramowicz, S Basu, A Barua - Cancers, 2023 - mdpi.com
Simple Summary Ovarian cancer (OVCA) is a fatal gynecological disease for which there is
no early detection test. Glucose-regulated protein 78 (GRP78), a protein marker of stress …

Death receptor 6 promotes ovarian cancer cell migration through KIF 11

B Shi, J Bao, Y Liu, J Shi - FEBS Open Bio, 2018 - Wiley Online Library
The expression of death receptor 6 (DR 6) is abnormal in some cancer types, but the
function and underlying molecular mechanisms of DR 6 in tumor progression are not yet …

Interleukin 16 expression changes in association with ovarian malignant transformation

A Yellapa, P Bitterman, S Sharma, AS Guirguis… - American journal of …, 2014 - Elsevier
Objective Long-term unresolved inflammation has been suggested as a risk factor for the
development of various malignancies. The goal of this study was to examine whether the …

Dietary Supplementation of Ashwagandha (Withania somnifera, Dunal) Enhances NK Cell Function in Ovarian Tumors in the Laying Hen Model of Spontaneous …

A Barua, MJ Bradaric, P Bitterman… - American Journal of …, 2013 - Wiley Online Library
Problem Ovarian cancer (OVCA) disseminates in a distinct pattern through peritoneal
metastasis and little is known about the immunosuppression in the tumor microenvironment …

Incidence of malignant transformation in the oviductal fimbria in laying hens, a preclinical model of spontaneous ovarian cancer

EA Paris, JM Bahr, P Bitterman, S Basu… - PLoS …, 2021 - journals.plos.org
Ovarian high grade serous carcinoma (HGSC) is a lethal form of ovarian cancer (OVCA). In
most cases it is detected at late stages as the symptoms are non-specific during early …

Interleukin 16‐(IL‐16‐) Targeted Ultrasound Imaging Agent Improves Detection of Ovarian Tumors in Laying Hens, a Preclinical Model of Spontaneous Ovarian …

A Barua, A Yellapa, JM Bahr, MK Adur… - BioMed research …, 2015 - Wiley Online Library
Limited resolution of transvaginal ultrasound (TVUS) scanning is a significant barrier to early
detection of ovarian cancer (OVCA). Contrast agents have been suggested to improve the …

VEGFR2-targeted ultrasound imaging agent enhances the detection of ovarian tumors at early stage in laying hens, a preclinical model of spontaneous ovarian …

A Barua, A Yellapa, JM Bahr, SA Machado… - Ultrasonic …, 2015 - journals.sagepub.com
Tumor-associated neoangiogenesis (TAN) is an early event in ovarian cancer (OVCA)
development. Increased expression of vascular endothelial growth factor receptor 2 …

Death receptor 6 as a prognostic marker in low-grade glioma

SK Stegmann, S Kuhl, NG Im, DT Diem-Dinh… - Anticancer …, 2022 - ar.iiarjournals.org
Background/Aim: Low-grade gliomas (LGG) are heterogenous tumours, causing variable
survivals in patients. Identifying molecular markers for a more accurate prognosis is …