Novel mechanisms in the pathogenesis of atrial fibrillation: practical applications

DH Lau, U Schotten, R Mahajan, NA Antic… - European heart …, 2016 - academic.oup.com
Intensive research over the last few decades has seen significant advances in our
understanding of the complex mechanisms underlying atrial fibrillation (AF). The epidemic of …

New findings in atrial fibrillation mechanisms

DH Lau, D Linz, P Sanders - Cardiac electrophysiology …, 2019 - cardiacep.theclinics.com
The pathophysiologic mechanisms underlying atrial fibrillation (AF) are highly complex and
variable among sufferers of this arrhythmia. 1, 2 This can be attributable to the different risk …

Current controversies in determining the main mechanisms of atrial fibrillation

U Schotten, D Dobrev, PG Platonov… - Journal of internal …, 2016 - Wiley Online Library
Despite considerable basic research into the mechanisms of atrial fibrillation (AF), not much
progress has been made in the prognosis of patients with AF. With the exception of …

Molecular mechanisms of atrial fibrosis: implications for the clinic

S Thanigaimani, DH Lau, T Agbaedeng… - Expert Review of …, 2017 - Taylor & Francis
Introduction: Recent research has unravelled an increasing list of cardiac conditions and risk
factors that may be responsible for the abnormal underlying atrial substrate that predisposes …

[HTML][HTML] German Cardiac Society Working Group on Cellular Electrophysiology state-of-the-art paper: impact of molecular mechanisms on clinical arrhythmia …

D Thomas, T Christ, L Fabritz, A Goette… - Clinical Research in …, 2019 - Springer
Cardiac arrhythmias remain a common challenge and are associated with significant
morbidity and mortality. Effective and safe rhythm control strategies are a primary, yet unmet …

[HTML][HTML] The role of microRNAs in antiarrhythmic therapy for atrial fibrillation

S Clauss, MF Sinner, S Kääb… - Arrhythmia & …, 2015 - ncbi.nlm.nih.gov
Atrial fibrillation (AF) is the most common arrhythmia worldwide and has an enormous
impact on our healthcare system as it is a major contributor of morbidity and mortality …

MicroRNAs as a diagnostic tool for heart failure and atrial fibrillation

LT Weckbach, U Grabmaier, S Clauss… - Current Opinion in …, 2016 - Elsevier
Highlights•miR423-5p discriminated patients with HF from those with other causes of
dyspnea.•miRNA-related pathophysiological mechanisms of AF were shown for miR-21 and …

[HTML][HTML] Reentry arrhythmia

A Goyal, H Basit, P Bhyan, R Zeltser - 2019 - europepmc.org
Objectives: Review the causes of reentry arrhythmias. Describe the electrocardiogram of a
patient with a reentry arrhythmia. Summarize the treatment options for reentry arrhythmias …

From translation to integration: how to approach the complexity of atrial fibrillation mechanisms

U Schotten - 2021 - academic.oup.com
Recent observations that early and aggressive rhythm control for atrial fibrillation (AF)
reduces adverse cardiovascular outcomes 1 and that catheter ablation may outperform anti …

[HTML][HTML] Inflammation and arrhythmogenesis: a narrative review of the complex relationship

A Taghdiri - International Journal of Arrhythmia, 2024 - Springer
Background A biological mechanism called inflammation is necessary for reacting to
damaging stimuli, but it can also, ironically, play a role in the formation of arrhythmias, or the …