Hydroxypropyl methylcellulose (HPMC) is an important polymeric excipient. Its versatility in
terms of molecular weights and viscosity grades is the basis for its wide and successful …

The pharmaceutical industry is undergoing a paradigm shift towards continuous processing
from batch, where continuous direct compression (CDC) is considered to offer the most …

In order to accurately determine the three-dimensional (3D) shape of granular particles, one
laborious approach is to employ X-ray microtomography and image processing techniques …

Within this study, tablets microstructure was investigated by X-ray microtomgraphy. The aim
was to gain information about their microstructure, and thus, derive deeper interpretation of …

The tableting of most pharmaceutical formulations requires the addition of lubricants to
reduce ejection forces, prevent tooling damage and tablet defects. The internal addition of …

Various studies investigate the predictability of the compressibility and compactibility of
tablet formulations based on the behaviour of the pure materials. However, these studies are …

This paper presents a case study on the first in-line application of AI-based image analysis
for real-time pharmaceutical particle size measurement in a continuous milling process. An …

Bonding area (BA) and bonding strength (BS) interplay dictates tensile strength of a tablet
and, hence, tabletability. Using a series of alkali halides with mechanical properties …

Tablet manufacturing involves the processing of raw materials through several unit
operations. Thus, the mitigation of input-induced variability should also consider the …

Cylindrical granules have been employed in the pharmaceutical industry. However, to our
knowledge, the study on the compressibility and tabletability of cylindrical granules has not …