Adrenal incidentaloma

M Sherlock, A Scarsbrook, A Abbas, S Fraser… - Endocrine …, 2020 - academic.oup.com
An adrenal incidentaloma is now established as a common endocrine diagnosis that
requires a multidisciplinary approach for effective management. The majority of patients can …

Global disorders of sex development update since 2006: perceptions, approach and care

PA Lee, A Nordenström, CP Houk, SF Ahmed… - Hormone research in …, 2016 - karger.com
The goal of this update regarding the diagnosis and care of persons with disorders of sex
development (DSDs) is to address changes in the clinical approach since the 2005 …

[HTML][HTML] Extraction methods of fat from food samples and preparation of fatty acid methyl esters for gas chromatography: A review

GG Hewavitharana, DN Perera, SB Navaratne… - Arabian Journal of …, 2020 - Elsevier
Global trends moved towards fast food consumption due to the busy lifestyle of humans.
Hence, the intake of fat-related food has exceeded the daily dietary reference intake (DRI) of …

The biosynthesis of enzymatically oxidized lipids

AA Hajeyah, WJ Griffiths, Y Wang, AJ Finch… - Frontiers in …, 2020 - frontiersin.org
Enzymatically oxidized lipids are a specific group of biomolecules that function as key
signaling mediators and hormones, regulating various cellular and physiological processes …

Recent advances and perspectives of metabolomics-based investigations in Parkinson's disease

Y Shao, W Le - Molecular neurodegeneration, 2019 - Springer
Parkinson's disease (PD) is the second most prevalent neurodegenerative disease of the
central nervous system (CNS), which affects mostly older adults. In recent years, the …

[HTML][HTML] Steroid metabolome analysis reveals prevalent glucocorticoid excess in primary aldosteronism

W Arlt, K Lang, AJ Sitch, AS Dietz, Y Rhayem… - JCI insight, 2017 - ncbi.nlm.nih.gov
BACKGROUND. Adrenal aldosterone excess is the most common cause of secondary
hypertension and is associated with increased cardiovascular morbidity. However, adverse …

[HTML][HTML] Intracrine androgen biosynthesis, metabolism and action revisited

L Schiffer, W Arlt, KH Storbeck - Molecular and cellular endocrinology, 2018 - Elsevier
Androgens play an important role in metabolic homeostasis and reproductive health in both
men and women. Androgen signalling is dependent on androgen receptor activation, mostly …

The art of measuring steroids: principles and practice of current hormonal steroid analysis

SA Wudy, G Schuler, A Sánchez-Guijo… - The Journal of steroid …, 2018 - Elsevier
Steroids are small and highly important structural or signalling molecules in living organisms
and their metabolism is complex. Due to the multiplicity of enzymes involved there are many …

Urine steroid metabolomics as a biomarker tool for detecting malignancy in adrenal tumors

W Arlt, M Biehl, AE Taylor, S Hahner… - The Journal of …, 2011 - academic.oup.com
Context: Adrenal tumors have a prevalence of around 2% in the general population.
Adrenocortical carcinoma (ACC) is rare but accounts for 2–11% of incidentally discovered …

Steroidogenesis: unanswered questions

WL Miller - Trends in Endocrinology & Metabolism, 2017 - cell.com
Until the mid-1980s studies of steroidogenesis largely depended on identifying steroid
structures and measuring steroid concentrations in body fluids. The molecular biology …