CeRebrUm and CardIac Protection with ALlopurinol in Neonates with Critical Congenital Heart Disease Requiring Cardiac Surgery with Cardiopulmonary Bypass …
R Stegeman, M Nijman, JMPJ Breur, F Groenendaal… - Trials, 2022 - Springer
Background Neonates with critical congenital heart disease (CCHD) undergoing cardiac
surgery with cardiopulmonary bypass (CPB) are at risk of brain injury that may result in …
surgery with cardiopulmonary bypass (CPB) are at risk of brain injury that may result in …
Efficacy and safety of febuxostat in the treatment of hyperuricemia in stable kidney transplant recipients
T Sofue, M Inui, T Hara, Y Nishijima… - Drug design …, 2014 - Taylor & Francis
Background Post-transplant hyperuricemia (PTHU), defined as serum uric acid
concentration≥ 7.0 mg/dL or need for treatment with allopurinol or benzbromarone, reduces …
concentration≥ 7.0 mg/dL or need for treatment with allopurinol or benzbromarone, reduces …
Allopurinol non-covalently facilitates binding of unconventional peptides to HLA-B* 58: 01
Allopurinol, widely used in gout treatment, is the most common cause of severe cutaneous
adverse drug reactions. The risk of developing such life-threatening reactions is increased …
adverse drug reactions. The risk of developing such life-threatening reactions is increased …
Atractylodin inhibits fructose-induced human podocyte hypermotility via anti-oxidant to down-regulate TRPC6/p-CaMK4 signaling
L Chen, YL Tang, ZH Liu, Y Pan, RQ Jiao… - European Journal of …, 2021 - Elsevier
High fructose has been reported to drive glomerular podocyte oxidative stress and then
induce podocyte foot process effacement in vivo, which could be partly regarded as …
induce podocyte foot process effacement in vivo, which could be partly regarded as …
Allopurinol augmentation in acute mania: a meta-analysis of placebo-controlled trials
AT Chen, T Malmstrom, HA Nasrallah - Journal of affective disorders, 2018 - Elsevier
Background Allopurinol is a xanthine oxidase inhibitor commonly used in the treatment of
gout. Recent studies have also shown its promise as an adjunctive treatment for manic …
gout. Recent studies have also shown its promise as an adjunctive treatment for manic …
[HTML][HTML] Occurrence, fate and potential risks of pharmaceuticals and personal care products (PPCPs) in Elbe river water during water treatment in Dresden, Germany
Y Adomat, T Grischek - Environmental Challenges, 2024 - Elsevier
Pharmaceuticals and personal care products (PPCPs) are found in most rivers facing
sewage input worldwide. This study investigated the occurence of 116 PPCPs in the Elbe …
sewage input worldwide. This study investigated the occurence of 116 PPCPs in the Elbe …
How much allopurinol does it take to get to target urate? Comparison of actual dose with creatinine clearance-based dose
LK Stamp, PT Chapman, ML Barclay, A Horne… - Arthritis research & …, 2018 - Springer
Objective Allopurinol dosing has frequently been limited based on creatinine clearance
(CrCL), resulting in failure to achieve target serum urate (SU). The aim of this analysis was to …
(CrCL), resulting in failure to achieve target serum urate (SU). The aim of this analysis was to …
Allopurinol attenuates postoperative pain and modulates the purinergic system in patients undergoing abdominal hysterectomy: a randomized controlled trial
AP Schmidt, ED de Oliveira, AC Fagundes… - Journal of …, 2021 - Springer
Purpose Allopurinol is a potent inhibitor of the enzyme xanthine oxidase used primarily in
the treatment of hyperuricemia and gout. The aim of this study was to compare the analgesic …
the treatment of hyperuricemia and gout. The aim of this study was to compare the analgesic …
Pharmacokinetic and pharmacodynamic interaction between allopurinol and probenecid in healthy subjects
SL Stocker, KM Williams, AJ McLachlan… - Clinical …, 2008 - Springer
Background and objective: Combination therapy with allopurinol and probenecid is used to
treat tophaceous gout in patients who do not respond sufficiently to allopurinol alone …
treat tophaceous gout in patients who do not respond sufficiently to allopurinol alone …
Cleroda-4(18),13-dien-15,16-olide as novel xanthine oxidase inhibitors: An integrated in silico and in vitro study
In the present study, in silico predictions and molecular docking were performed on five
clerodane diterpenes (1–5) from Polyalthia longifolia seeds to evaluate their potential as …
clerodane diterpenes (1–5) from Polyalthia longifolia seeds to evaluate their potential as …