Approximately 35% of patients with colorectal cancer (CRC) have a family history of the
disease attributed to genetic factors, common exposures, or both. Some families with a …

Colonoscopy is performed routinely for colorectal cancer (CRC) screening, follow-up of
other abnormal screening tests, workup of signs and symptoms of gastrointestinal disease …

ESGE recommends that individuals with Lynch syndrome should be followed in dedicated
units that practice monitoring of compliance and endoscopic performance measures. Strong …

The concept of colorectal cancer (CRC) screening has transformed over the past few
decades, with the realization that the benefit is primarily from prevention of cancer via …

Importance Guidelines recommend a 10-year rescreening interval after a colonoscopy with
normal findings (negative colonoscopy results), but evidence supporting this …

Background It remains unknown whether the benefit of colonoscopy screening against
colorectal cancer (CRC) and the optimal age to start screening differ by CRC risk profile …

Background & Aims Colorectal cancer (CRC) incidence at ages younger than 50 years is
increasing, leading to proposals to lower the CRC screening initiation age to 45 years. Data …

Background & Aims Polygenic risk scores (PRSs) could help to define starting ages for
colorectal cancer (CRC) screening. However, the role of PRS in determining the length of …

The introduction of average-risk colorectal cancer (CRC) screening programs means that
many subjects with family history of CRC and without well-described inherited syndromes …

Importance For individuals without a family history of colorectal cancer (CRC), colonoscopy
screening every 10 years is recommended to reduce CRC incidence and mortality …