New antimalarial targets are the prime need for the discovery of potent drug candidates. In
order to fulfill this objective, antimalarial drug researches are focusing on promising targets …

Vector-borne illnesses comprise a significant portion of human maladies, representing 17%
of global infections. Transmission of vector-borne pathogens to mammals primarily occurs …

Toxoplasma is an obligate intracellular parasite that replicates in mammalian cells within a
parasitophorous vacuole (PV) that does not fuse with any host organelles. One mechanism …

Lipid droplets (lipid bodies, LDs) are dynamic organelles that have important roles in
regulating lipid metabolism, energy homeostasis, cell signaling, membrane trafficking, and …

Phospholipid metabolism is crucial for membrane biogenesis and homeostasis of
Plasmodium falciparum. To generate such phospholipids, the parasite extensively …

Information on the growth rate and metabolism of microbial pathogens that cause long-term
chronic infections is limited, reflecting the absence of suitable tools for measuring these …

Protein myristoylation is a C14 fatty acid modification found in all living organisms.
Myristoylation tags either the N-terminal alpha groups of cysteine or glycine residues …

Plasmodium gene functions in mosquito and liver stages remain poorly characterized due to
limitations in the throughput of phenotyping at these stages. To fill this gap, we followed …

The prodigious rate at which malaria parasites proliferate during asexual blood-stage
replication, midgut sporozoite production, and intrahepatic development creates a …

The seawater microalga Nannochloropsis gaditana is capable of accumulating a large
fraction of reduced carbon as lipids. To clarify the molecular bases of this metabolic feature …