Endometrial function in women with polycystic ovary syndrome: a comprehensive review

S Palomba, TT Piltonen… - Human reproduction …, 2021 - academic.oup.com
BACKGROUND Polycystic ovary syndrome (PCOS) is the most common cause of
anovulatory infertility. An endometrial component has been suggested to contribute to …

Role of nuclear progesterone receptor isoforms in uterine pathophysiology

B Patel, S Elguero, S Thakore… - Human reproduction …, 2015 - academic.oup.com
BACKGROUND Progesterone is a key hormonal regulator of the female reproductive
system. It plays a major role to prepare the uterus for implantation and in the establishment …

Is fertility reduced in ovulatory women with polycystic ovary syndrome? An opinion paper

S Palomba - Human Reproduction, 2021 - academic.oup.com
Polycystic ovary syndrome (PCOS) is the most common cause of anovulatory infertility;
however, whether women with PCOS and spontaneous or drug-induced ovulatory cycles …

Fertile ground: human endometrial programming and lessons in health and disease

J Evans, LA Salamonsen, A Winship… - Nature Reviews …, 2016 - nature.com
The human endometrium is a highly dynamic tissue that is cyclically shed, repaired,
regenerated and remodelled, primarily under the orchestration of oestrogen and …

Endocrine regulation of menstruation

HN Jabbour, RW Kelly, HM Fraser… - Endocrine …, 2006 - academic.oup.com
In women, endometrial morphology and function undergo characteristic changes every
menstrual cycle. These changes are crucial for perpetuation of the species and are …

The Science behind 25 Years of Ovarian Stimulation for in Vitro Fertilization

NS Macklon, RL Stouffer, LC Giudice… - Endocrine …, 2006 - academic.oup.com
To allow selection of embryos for transfer after in vitro fertilization, ovarian stimulation is
usually carried out with exogenous gonadotropins. To compensate for changes induced by …

Molecular phenotyping of human endometrium distinguishes menstrual cycle phases and underlying biological processes in normo-ovulatory women

S Talbi, AE Hamilton, KC Vo, S Tulac… - …, 2006 - academic.oup.com
Histological evaluation of endometrium has been the gold standard for clinical diagnosis
and management of women with endometrial disorders. However, several recent studies …

Self-renewing endometrial epithelial organoids of the human uterus

HC Fitzgerald, P Dhakal, SK Behura… - Proceedings of the …, 2019 - National Acad Sciences
The human endometrium is essential in providing the site for implantation and maintaining
the growth and survival of the conceptus. An unreceptive endometrium and disrupted …

[HTML][HTML] Differential gene regulation by the two progesterone receptor isoforms in human breast cancer cells

JK Richer, BM Jacobsen, NG Manning, MG Abel… - Journal of Biological …, 2002 - ASBMB
The PR-A and PR-B isoforms of progesterone receptors (PR) have different physiological
functions, and their ratio varies widely in breast cancers. To determine whether the two PR …

The human endometrium as a fertility-determining factor

T Strowitzki, A Germeyer, R Popovici… - Human reproduction …, 2006 - academic.oup.com
Intensive research work has been performed to better understand the regulation of the
endometrium and its clinical implications to improve implantation. Although many proteins …