A newborn infant with ambiguous genitalia is a complex enough problem to unravel without
any further clouding by confusing terms. The nomenclature 'intersex','hermaphrodite'and …

Spermatogenesis involves the aggregated action of up to 2300 genes, any of which, could,
potentially, provide targets for diagnostic tests of male factor infertility. Contrary to the …

Background and objectives: XX male syndrome is part of the disorders of sex development
(DSD). The patients generally have normal external genitalia and discover their pathology in …

Klinefelter syndrome (KS) describes the phenotype of the most common sex chromosome
abnormality in humans and occurs in one of every 600 newborn males. The typical …

Infertility affects approximately 15% of couples, and male factor is responsible for 30%–50%
of all infertility. The most severe form of male infertility is testicular failure, and the typical …

Approximately 1 in 6 couples in the Western world is not able to conceive spontaneously
after 1 year of unprotected intercourse; in nearly half of these couples, the male partner has …

Sexual differentiation is the result of complex genetic and endocrine mechanisms that are
closely associated with the development of both the genitourinary system and the adrenal …

Forty-six XX disorder of sex development is an uncommon medical condition observed at
times during the evaluation of a man's fertility. The following is a case series and literature …

PURPOSE: To determine the frequency of genetic alterations in a population of Brazilian
infertile men with severe oligozoospermia or non-obstructive azoospermia. MATERIALS …

The 46, XX male disorder of sex development (DSD) is a rare genetic condition. Here, we
report the case of a 46, XX SRY-negative male with complete masculinization. The coding …