Exosome engineering in cell therapy and drug delivery

S Sadeghi, FR Tehrani, S Tahmasebi, A Shafiee… - …, 2023 - Springer
Cell-derived exosomes have opened new horizons in modern therapy for advanced drug
delivery and therapeutic applications, due to their key features such as low immunogenicity …

Extracellular vesicles: Emerging frontiers in wound healing

MD Hade, CN Suire, J Mossell… - Medicinal Research …, 2022 - Wiley Online Library
Extracellular vesicles are membranous particles, ranging from 30 nm to 10 µm in diameter,
which are released by nearly all cell types to aid in intercellular communication. These …

Biomembrane-based nanostructures for cancer targeting and therapy: from synthetic liposomes to natural biomembranes and membrane-vesicles

J Wang, M Zhu, G Nie - Advanced drug delivery reviews, 2021 - Elsevier
The translational success of liposomes in chemotherapeutics has already demonstrated the
great potential of biomembrane-based nanostructure in effective drug delivery. Meanwhile …

[HTML][HTML] Nanocarriers for pancreatic cancer imaging, treatments, and immunotherapies

L Liu, PG Kshirsagar, SK Gautam, M Gulati, EI Wafa… - Theranostics, 2022 - ncbi.nlm.nih.gov
Pancreatic tumors are highly desmoplastic and immunosuppressive. Delivery and
distribution of drugs within pancreatic tumors are compromised due to intrinsic physical and …

[HTML][HTML] Cryogenic 3D printed hydrogel scaffolds loading exosomes accelerate diabetic wound healing

Y Hu, B Wu, Y Xiong, R Tao, AC Panayi, L Chen… - Chemical Engineering …, 2021 - Elsevier
Diabetic wounds represent a pressing concern affecting the health and quality of life of
patients. Despite the continuous improvement in therapeutic strategy, diabetic wounds …

Bioengineered exosomal-membrane-camouflaged abiotic nanocarriers: neurodegenerative diseases, tissue engineering and regenerative medicine

D Lopes, J Lopes, M Pereira-Silva, D Peixoto… - Military Medical …, 2023 - Springer
A bio-inspired strategy has recently been developed for camouflaging nanocarriers with
biomembranes, such as natural cell membranes or subcellular structure-derived …

Exosomes engineering and their roles as therapy delivery tools, therapeutic targets, and biomarkers

N Kučuk, M Primožič, Ž Knez, M Leitgeb - International journal of …, 2021 - mdpi.com
Exosomes are becoming increasingly important therapeutic biomaterials for use in a variety
of therapeutic applications due to their unique characteristics, especially due to the …

An effective peptide-based platform for efficient exosomal loading and cellular delivery of a microRNA

MD Hade, CN Suire, Z Suo - ACS Applied Materials & Interfaces, 2023 - ACS Publications
Exosomes, membrane-bound nanosized vesicles of biologic origin, are known to contain
various molecules, eg, proteins, lipids, and nucleic acids, which contribute to the exosomes' …

Exosome-based drug delivery systems and their therapeutic applications

J Lee, JH Lee, K Chakraborty, J Hwang, YK Lee - RSC advances, 2022 - pubs.rsc.org
In the past few decades, scientists have actively worked on developing effective drug
delivery systems (DDSs) as means to control life-threatening diseases and challenging …

NK cell-derived exosomes enhance the anti-tumor effects against ovarian cancer by delivering cisplatin and reactivating NK cell functions

H Luo, Y Zhou, J Zhang, Y Zhang, S Long… - Frontiers in …, 2023 - frontiersin.org
Exosomes are membranous vesicles actively secreted by almost all cells and they deliver
certain intracellular molecules, including nucleic acids, proteins, and lipids, to target cells …