Fibrinogen conversion into insoluble fibrin and the formation of a stable clot is the final step
of the coagulation cascade. Fibrin clot porosity and its susceptibility to plasmin-mediated …

Significance: Aging is a complex process associated with an increased risk of many
diseases, including thrombosis. This review summarizes age-related prothrombotic …

Background Type 2 diabetes mellitus (T2DM) patients are at high risk of cardiovascular (CV)
events. Factor XI (FXI) is associated with arterial thromboembolism, including myocardial …

Background Multiple pleiotropic effects of statins include antithrombotic properties with
formation of looser fibrin networks more susceptible to lysis. Recently, rosuvastatin 20 mg/d …

Abstract Introduction Neutrophil extracellular traps (NETs) formation contributes to
thrombosis but its role in atrial fibrillation (AF) is poorly explored. We investigated whether …

BACKGROUND: Acute ischemic stroke (AIS) is associated with enhanced oxidative stress
and unfavorably altered fibrin clot properties. We investigated determinants of plasma …

In this work, we fabricated rutin (RTN)-loaded albumin nanoparticles (RTN-ALB-NPs) and
abciximab (ABX) coated RTN-loaded albumin nanoparticles (ABX-RTN-ALB-NPs) for the …

Background Metabolic-associated fatty liver disease (MAFLD), one of the most common liver
diseases, is detected in patients with concomitant hepatic steatosis and Type 2 Diabetes …

Introduction Patients with coronary artery disease (CAD) display a prothrombotic fibrin clot
phenotype, involving low permeability and resistance to lysis. The determinants of this …

Bioactive glasses (BGs) are among the most popular biomaterial categories. Due to their
biocompatibility, bioactivity, antimicrobial, and angiogenesis abilities, they are increasingly …