The unique properties of carbon nanotubes (CNTs)(such as their high surface to volume
ratios, enhanced conductivity and strength, biocompatibility, ease of functionalization, optical …

The immune system and cancer have a complex relationship with the immune system
playing a dual role in tumor development. The effector cells of the immune system can …

Forming the inner layer of the vascular system, endothelial cells (ECs) facilitate a multitude
of crucial physiological processes throughout the body. Vascular ECs enable the vessel wall …

Both immune checkpoint inhibitors (ICI) and antiangiogenesis agents have changed the
landscape of cancer treatment in the modern era. While antiangiogenesis agents have …

Simple Summary Integrins, a superfamily of cell adhesion receptors, were extensively
investigated as therapeutic targets over the last decades, motivated by their multiple …

Integrins are key regulators of communication between cells and with their
microenvironment. Eight members of the integrin superfamily recognize the tripeptide motif …

The extracellular matrix (ECM) is a ubiquitous member of the body and is key to the
maintenance of tissue and organ integrity. Initially thought to be a bystander in many cellular …

During metastasis, cancer cells disseminate to other parts of the body by entering the
bloodstream in a process that is called intravasation. They then extravasate at metastatic …

In vivo screening of phage libraries in tumor-bearing mice has been used to identify
peptides that direct phage homing to a tumor. The power of in vivo phage screening is …

Nanomedicine is an emerging form of therapy that focuses on alternative drug delivery and
improvement of the treatment efficacy while reducing detrimental side effects to normal …