Macrophage cell membrane‐cloaked nanoplatforms for biomedical applications

J Lopes, D Lopes, M Pereira‐Silva, D Peixoto… - Small …, 2022 - Wiley Online Library
Biomimetic approaches utilize natural cell membrane‐derived nanovesicles to camouflage
nanoparticles to circumvent some limitations of nanoscale materials. This emergent cell …

Functional hallmarks of healthy macrophage responses: their regulatory basis and disease relevance

KM Sheu, A Hoffmann - Annual review of immunology, 2022 - annualreviews.org
Macrophages are first responders for the immune system. In this role, they have both effector
functions for neutralizing pathogens and sentinel functions for alerting other immune cells of …

The promising role of tumor-associated macrophages in the treatment of cancer

H Wang, X Wang, X Zhang, W Xu - Drug Resistance Updates, 2024 - Elsevier
Macrophages are important components of the immune system. Mature macrophages can
be recruited to tumor microenvironment that affect tumor cell proliferation, invasion and …

[HTML][HTML] Comparison of monocytic cell lines U937 and THP-1 as macrophage models for in vitro studies

CR Nascimento, NAR Fernandes… - … and Biophysics Reports, 2022 - Elsevier
Understanding macrophage biology can improve comprehension of diverse biological
processes and provide insights into novel therapeutic immunomodulatory strategies. Due to …

Lipid-Laden Macrophages and Inflammation in Atherosclerosis and Cancer: An Integrative View

M Lee-Rueckert, J Lappalainen, PT Kovanen… - Frontiers in …, 2022 - frontiersin.org
Atherosclerotic arterial plaques and malignant solid tumors contain macrophages, which
participate in anaerobic metabolism, acidosis, and inflammatory processes inherent in the …

The evolving roles of cardiac macrophages in homeostasis, regeneration, and repair

S Alvarez-Argote, CC O'Meara - International journal of molecular …, 2021 - mdpi.com
Macrophages were first described as phagocytic immune cells responsible for maintaining
tissue homeostasis by the removal of pathogens that disturb normal function. Historically …

Imaging dendritic cell functions

B Bošnjak, KTH Do, R Förster… - Immunological …, 2022 - Wiley Online Library
Dendritic cells (DCs) are crucial for the appropriate initiation of adaptive immune responses.
During inflammation, DCs capture antigens, mature, and migrate to lymphoid tissues to …

Targeting monocytes/macrophages in fibrosis and cancer diseases: Therapeutic approaches

E Conte - Pharmacology & Therapeutics, 2022 - Elsevier
Over almost 140 years since their identification, the knowledge about macrophages has
unbelievably evolved. The'big eaters' from being thought of as simple phagocytic cells have …

Macrophage metabolism in nonalcoholic fatty liver disease

W Zhang, R Lang - Frontiers in Immunology, 2023 - frontiersin.org
Nonalcoholic fatty liver disease (NAFLD) and its inflammatory and often progressive subtype
nonalcoholic steatohepatitis (NASH), have emerged as significant contributors to hepatic …

Tumour‐associated macrophages in gastric cancer: From function and mechanism to application

J Li, J Sun, Z Zeng, Z Liu, M Ma, Z Zheng… - Clinical and …, 2023 - Wiley Online Library
Background Gastric cancer (GC) is a malignant tumour, with high morbidity and mortality
rates worldwide. The occurrence and development of GC is a complex process involving …