Effects of uric acid on diabetes mellitus and its chronic complications

Q Xiong, J Liu, Y Xu - International journal of endocrinology, 2019 - Wiley Online Library
With the deepening of the researches on uric acid, especially in the study of metabolic
diseases, uric acid has been found to be closely related to obesity, metabolic syndrome …

Renal hyperfiltration in adolescents with type 2 diabetes: physiology, sex differences, and implications for diabetic kidney disease

P Bjornstad, DZ Cherney - Current diabetes reports, 2018 - Springer
Abstract Purpose of Review Compared to adult-onset type 2 diabetes (T2D), youth with T2D
have a more aggressive phenotype with greater insulin resistance (IR), more rapid β cell …

[HTML][HTML] Dapagliflozin in focal segmental glomerulosclerosis: a combined human-rodent pilot study

H Rajasekeran, HN Reich… - American Journal …, 2018 - journals.physiology.org
Focal segmental glomerulosclerosis (FSGS) is an important cause of nondiabetic chronic
kidney disease (CKD). Sodium-glucose cotransporter 2 inhibition (SGLT2i) therapy …

The impact of sotagliflozin on renal function, albuminuria, blood pressure, and hematocrit in adults with type 1 diabetes

DH van Raalte, P Bjornstad, F Persson… - Diabetes …, 2019 - Am Diabetes Assoc
OBJECTIVE In people with type 2 diabetes, sodium–glucose cotransporter 2 inhibitors
(SGLT2i) reduce cardiovascular risk and progression of diabetic kidney disease. Our aim …

Elevated serum uric acid level predicts rapid decline in kidney function

M Kuwabara, P Bjornstad, I Hisatome, K Niwa… - American journal of …, 2017 - karger.com
Background: While elevated serum uric acid level (SUA) is a recognized risk factor for
chronic kidney disease, it remains unclear whether change in SUA is independently …

Initial eGFR changes with ertugliflozin and associations with clinical parameters: analyses from the VERTIS CV trial

DZI Cherney, F Cosentino, S Dagogo-Jack… - American Journal of …, 2022 - karger.com
Introduction: Using data from the ertugliflozin cardiovascular outcomes trial in patients with
type 2 diabetes mellitus (VERTIS CV; NCT01986881), associations between the initial …

[HTML][HTML] Novel therapies for diabetic kidney disease

DZI Cherney, GL Bakris - Kidney International Supplements, 2018 - Elsevier
Over the past 30 years there have been many complementary therapies developed to
achieve glycemic control and have an impact on cardiovascular outcomes, as well as …

The Gomez equations and renal hemodynamic function in kidney disease research

P Bjornstad, M Škrtić, Y Lytvyn… - American Journal …, 2016 - journals.physiology.org
Diabetic kidney disease (DKD) remains the leading cause of end-stage renal disease. A
major challenge in preventing DKD is the difficulty in identifying high-risk patients at a …

The correlation between serum uric acid and diabetic kidney disease in type 1 diabetes patients in Anhui, China

J Jiang, X Zhou, L Lan, W Ren - BMC nephrology, 2023 - Springer
Abstract Background/Aim To assess the correlation between serum uric acid (UA) level and
diabetic kidney disease (DKD) in Type 1 diabetes (T1DM) patients in Anhui, China. Methods …

Renal and vascular effects of uric acid lowering in normouricemic patients with uncomplicated type 1 diabetes

Y Lytvyn, R Har, A Locke, V Lai, D Fong, A Advani… - Diabetes, 2017 - Am Diabetes Assoc
Higher plasma uric acid (PUA) levels are associated with lower glomerular filtration rate
(GFR) and higher blood pressure (BP) in patients with type 1 diabetes (T1D). Our aim was to …