Discontinuation, suboptimal adherence, and reinitiation of oral HIV pre-exposure prophylaxis: a global systematic review and meta-analysis
Background Poor adherence to oral HIV pre-exposure prophylaxis (PrEP) diminishes its
clinical and public health benefits. This study synthesises evidence regarding …
clinical and public health benefits. This study synthesises evidence regarding …
Barriers to the wider use of pre-exposure prophylaxis in the United States: a narrative review
Antiretroviral pre-exposure prophylaxis (PrEP) to prevent HIV transmission was first
approved by the US Food and Drug Administration in 2012. Despite correlations of …
approved by the US Food and Drug Administration in 2012. Despite correlations of …
Emtricitabine and tenofovir alafenamide vs emtricitabine and tenofovir disoproxil fumarate for HIV pre-exposure prophylaxis (DISCOVER): primary results from a …
KH Mayer, JM Molina, MA Thompson, PL Anderson… - The Lancet, 2020 - thelancet.com
Background Tenofovir alafenamide shows high antiviral efficacy and improved renal and
bone safety compared with tenofovir disoproxil fumarate when used for HIV treatment. Here …
bone safety compared with tenofovir disoproxil fumarate when used for HIV treatment. Here …
Antiretroviral drugs for treatment and prevention of HIV infection in adults: 2018 recommendations of the International Antiviral Society–USA Panel
MS Saag, CA Benson, RT Gandhi, JF Hoy… - Jama, 2018 - jamanetwork.com
Importance Antiretroviral therapy (ART) is the cornerstone of prevention and management of
HIV infection. Objective To evaluate new data and treatments and incorporate this …
HIV infection. Objective To evaluate new data and treatments and incorporate this …
Association of HIV preexposure prophylaxis with incidence of sexually transmitted infections among individuals at high risk of HIV infection
Importance Emerging evidence suggests that risk of bacterial sexually transmitted infections
(STIs) increases among gay and bisexual men following initiation of HIV preexposure …
(STIs) increases among gay and bisexual men following initiation of HIV preexposure …
Sexually transmitted infections: challenges ahead
WHO estimated that nearly 1 million people become infected every day with any of four
curable sexually transmitted infections (STIs): chlamydia, gonorrhoea, syphilis, and …
curable sexually transmitted infections (STIs): chlamydia, gonorrhoea, syphilis, and …
Viral suppression and HIV transmission in serodiscordant male couples: an international, prospective, observational, cohort study
Background Evidence on viral load and HIV transmission risk in HIV-serodiscordant male
homosexual couples is limited to one published study. We calculated transmission rates in …
homosexual couples is limited to one published study. We calculated transmission rates in …
On-demand preexposure prophylaxis in men at high risk for HIV-1 infection
JM Molina, C Capitant, B Spire, G Pialoux… - … England Journal of …, 2015 - Mass Medical Soc
Background Antiretroviral preexposure prophylaxis has been shown to reduce the risk of
human immunodeficiency virus type 1 (HIV-1) infection in some studies, but conflicting …
human immunodeficiency virus type 1 (HIV-1) infection in some studies, but conflicting …
[HTML][HTML] Artificial intelligence and the implementation challenge
Background Applications of artificial intelligence (AI) in health care have garnered much
attention in recent years, but the implementation issues posed by AI have not been …
attention in recent years, but the implementation issues posed by AI have not been …
Efficacy, safety, and effect on sexual behaviour of on-demand pre-exposure prophylaxis for HIV in men who have sex with men: an observational cohort study
Background Data for on-demand pre-exposure prophylaxis (PrEP) are scarce. We
implemented a cohort study to assess its efficacy, safety, and effect on sexual behaviour …
implemented a cohort study to assess its efficacy, safety, and effect on sexual behaviour …