Recent advances in contrast-enhanced photoacoustic imaging: overcoming the physical and practical challenges
For decades now, photoacoustic imaging (PAI) has been investigated to realize its potential
as a niche biomedical imaging modality. Despite its highly desirable optical contrast and …
as a niche biomedical imaging modality. Despite its highly desirable optical contrast and …
Strategic design of conquering hypoxia in tumor for advanced photodynamic therapy
C Zhang, X Hu, L Jin, L Lin, H Lin… - Advanced Healthcare …, 2023 - Wiley Online Library
Photodynamic therapy (PDT), with its advantages of high targeting, minimally invasive, and
low toxicity side effects, has been widely used in the clinical therapy of various tumors …
low toxicity side effects, has been widely used in the clinical therapy of various tumors …
Metabolic reprogramming mediated PD-L1 depression and hypoxia reversion to reactivate tumor therapy
As a promising cancer treatment, photodynamic therapy (PDT) still achieved limited clinical
success due to the severe hypoxia and programmed death ligand-1 (PD-L1) over-expressed …
success due to the severe hypoxia and programmed death ligand-1 (PD-L1) over-expressed …
Dual‐Responsive Nanocomposites for Synergistic Antibacterial Therapies Facilitating Bacteria‐Infected Wound Healing
The rising dangers of bacterial infections have created an urgent need for the development
of a new generation of antibacterial technologies and therapeutics. Antibacterial …
of a new generation of antibacterial technologies and therapeutics. Antibacterial …
Photoactivatable immunostimulatory nanomedicine for immunometabolic cancer therapy
W Wu, Y Pu, B Zhou, Y Shen, S Gao… - Journal of the …, 2022 - ACS Publications
A rationally designed immunostimulant (CC@ SiO2-PLG) with a photoactivatable
immunotherapeutic function for synergetic tumor therapy is reported. This CC@ SiO2-PLG …
immunotherapeutic function for synergetic tumor therapy is reported. This CC@ SiO2-PLG …
Biocatalytic depletion of tumorigenic energy sources driven by cascade reactions for efficient antitumor therapy
Glucose and lactate play important roles for tumor growth. How to simultaneously deprive
tumors of glucose and lactate is a big challenge. We have developed a cascade catalytic …
tumors of glucose and lactate is a big challenge. We have developed a cascade catalytic …
Killing three birds with one stone: Multi-stage metabolic regulation mediated by clinically usable berberine liposome to overcome photodynamic immunotherapy …
C Zheng, W Luo, Y Liu, J Chen, H Deng, Z Zhou… - Chemical Engineering …, 2023 - Elsevier
Nowadays, photodynamic therapy (PDT) has become a novel effect modality for cancer
therapy. But, facing the extremely hypoxic tumor microenvironment, the efficacy of PDT is still …
therapy. But, facing the extremely hypoxic tumor microenvironment, the efficacy of PDT is still …
Heptamethine Cyanine‐Based Nanotheranostics with Catalase‐Like Activity for Synergistic Phototherapy of Cancer
M Liang, X Mu, Y Li, Y Tan, X Hao… - Advanced Functional …, 2023 - Wiley Online Library
Single‐molecule photosensitizers (PSs) for synergistic phototherapy are desirable but highly
challenging, due to the competitive relationship between photothermal (PTT) and …
challenging, due to the competitive relationship between photothermal (PTT) and …
Nanoparticles mediated tumor microenvironment modulation: current advances and applications
The tumor microenvironment (TME) plays a key role in cancer development and emergence
of drug resistance. TME modulation has recently garnered attention as a potential approach …
of drug resistance. TME modulation has recently garnered attention as a potential approach …
Recent advances in strategies for addressing hypoxia in tumor photodynamic therapy
L Hong, J Li, Y Luo, T Guo, C Zhang, S Ou, Y Long… - Biomolecules, 2022 - mdpi.com
Photodynamic therapy (PDT) is a treatment modality that uses light to target tumors and
minimize damage to normal tissues. It offers advantages including high spatiotemporal …
minimize damage to normal tissues. It offers advantages including high spatiotemporal …