Nitric Oxide (NO) is a small molecule that continues to attract much attention from the
scientific community. Since its discovery, it has been evident that NO has a crucial role in the …

Patients with tension-type headache (TTH) have an increased risk of developing arterial
hypertension (AH), while hypertensive subjects do seem to have an increased risk of TTH …

The SARS-CoV2 is a highly contagious pathogen that causes COVID-19 disease. It has
affected millions of people globally with an average lethality of~ 3%. There is an urgent need …

The aim of this review article is to summarize the current knowledge about mechanisms that
connect blood pressure regulation and hypercholesterolemia, the mutual interaction …

Cardiovascular disease (CVD), such as stroke, ischemic heart disease, and heart failure,
accounts for many deaths, and its increasing incidence is a worldwide concern …

β-blockers is a vast group of antiarrhythmic drugs which differ in their pharmacokinetic and
chemical properties. Some of them block β-adrenergic receptors selectively while the others …

There is evidence that H2R blockade improves ischemia/reperfusion (I/R) injury, but the
underlying cellular mechanisms remain unclear. Histamine is known to increase vascular …

Heart failure with preserved ejection fraction (HFpEF) is a complex heterogeneous disease
characterized by autonomic imbalance, cardiac remodeling, and diastolic dysfunction. One …

Chronic kidney disease (CKD) affects 8–16% of the population worldwide and is
characterized by fibrotic processes. Understanding the cellular and molecular mechanisms …

Hypertension is one of the leading risk factors for morbidity and mortality in patients with
cardiovascular and cerebrovascular diseases and renal impairment. It also leads to target …