Immunotherapy that harnesses the human immune system to fight cancer has received
widespread attention and become a mainstream strategy for cancer treatment. Cancer …

As a promising alternative platform for cellular immunotherapy, natural killer cells (NK) have
recently gained attention as an important type of innate immune regulatory cell. NK cells can …

Trogocytosis is an active process that transfers surface material from targeted to effector
cells. Using multiple in vivo tumor models and clinical data, we report that chimeric antigen …

Cancer immunotherapy has been firmly established as a new milestone for cancer therapy,
with the development of multiple immune cells as therapeutic tools. Natural killer (NK) cells …

Chimeric antigen receptors (CARs) significantly enhance the anti-tumor activity of immune
effector cells. Although most studies have evaluated CAR expression in T cells, here we …

Nature has always inspired robotic designs and concepts. It is conceivable that biomimic
nanorobots will soon play a prominent role in medicine. The “Terminator” in the science …

Gloss PD-L1 and PD-1 (PD) pathway blockade is a highly promising therapy and has
elicited durable antitumor responses and long-term remissions in a subset of patients with a …

Natural killer (NK) cells are lymphocytes with important roles in innate and adaptive immune
responses to tumours and viral infection. However, in certain chronic diseases, including …

Abstract Vγ9Vδ2 T cells are promising candidates for cellular tumor immunotherapy. Due to
their HLA-independent mode of action, allogeneic Vγ9Vδ2 T cells can be considered for …

Natural killer (NK) cells are a critical component of the innate immune system. Chimeric
antigen receptors (CARs) re-direct NK cells toward tumor cells carrying corresponding …