Preclinical animal studies provide valuable opportunities to better understand human
diseases and contribute to major advances in medicine. This review provides a …

The precorneal tear film is classically described as a trilaminar structure adherent to and
covering the external cornea, forming an integral and important physicochemical component …

Purpose: Compare the precision of doxycycline quantification in tear fluid collected with
either Schirmer strips or polyvinyl acetal (PVA) sponges following oral drug administration …

Antimicrobial activity and post-antibiotic effects (PAEs) are both important parameters in
determination of the dosage regimen of antimicrobial agents. In the present study …

OBJECTIVE To compare the efficacy of various concentrations and combinations of serum,
EDTA, 3 tetracyclines, and N-acetylcysteine (NAC) for collagenase inhibition in an in vitro …

Purpose Describe the pharmacokinetics of extended-release parenteral ceftiofur (Excede®)
in canine tear film and compare these concentrations to minimal inhibitory concentrations …

Ulcerative keratitis and keratomalacia in horses: Medical management and surgical
considerations Page 1 Clinical Commentary Ulcerative keratitis and keratomalacia in horses …

Paper spray high-resolution accurate mass spectrometry is a fast and versatile analysis
method. This ambient ionization technique enables the quantitation of xenobiotics in …

Case history: Gradual onset of ocular opacity was observed in three gold-striped geckos
(Woodworthia chrysosiretica), and five Pacific geckos (Dactylocnemis pacificus) held in two …

Background Ulcerative bacterial keratitis can result in loss of vision or the eye. Antimicrobial
susceptibility data are essential in selecting optimal therapy while pending culture results …