Growth factors, PI3K/AKT/mTOR and MAPK signaling pathways in colorectal cancer pathogenesis: where are we now?

C Stefani, D Miricescu, II Stanescu-Spinu… - International journal of …, 2021 - mdpi.com
Colorectal cancer (CRC) is a predominant malignancy worldwide, being the fourth most
common cause of mortality and morbidity. The CRC incidence in adolescents, young adults …

[HTML][HTML] Proton pump inhibitors and dysbiosis: Current knowledge and aspects to be clarified

G Bruno, P Zaccari, G Rocco, G Scalese… - World journal of …, 2019 - ncbi.nlm.nih.gov
Proton pump inhibitors (PPIs) are common medications within the practice of
gastroenterology. These drugs, which act through the irreversible inhibition of the …

Enteric fungal microbiota dysbiosis and ecological alterations in colorectal cancer

OO Coker, G Nakatsu, RZ Dai, WKK Wu, SH Wong… - Gut, 2019 - gut.bmj.com
Objectives Bacteriome and virome alterations are associated with colorectal cancer (CRC).
Nevertheless, the gut fungal microbiota in CRC remains largely unexplored. We aimed to …

The microbiome and human biology

R Knight, C Callewaert, C Marotz… - Annual review of …, 2017 - annualreviews.org
Over the past few years, microbiome research has dramatically reshaped our understanding
of human biology. New insights range from an enhanced understanding of how microbes …

Gut microbiota in colorectal cancer: biological role and therapeutic opportunities

H Pandey, DWT Tang, SH Wong, D Lal - Cancers, 2023 - mdpi.com
Simple Summary Colorectal cancer (CRC) is the second-leading cause of cancer-related
deaths worldwide. In this review article, we examine the role of gut microbiota in the …

Dysbiosis signatures of gut microbiota in coronary artery disease

Q Zhu, R Gao, Y Zhang, D Pan, Y Zhu… - Physiological …, 2018 - journals.physiology.org
Gut microbiota dysbiosis has been considered to be an important risk factor that contributes
to coronary artery disease (CAD), but limited evidence exists about the involvement of gut …

Exploring the role of gut microbiome in colon cancer

I Chattopadhyay, R Dhar, K Pethusamy… - Applied biochemistry …, 2021 - Springer
Dysbiosis of the gut microbiome has been associated with the development of colorectal
cancer (CRC). Gut microbiota is involved in the metabolic transformations of dietary …

Therapeutic methods of gut microbiota modification in colorectal cancer management–fecal microbiota transplantation, prebiotics, probiotics, and synbiotics

K Kaźmierczak-Siedlecka, A Daca, M Fic… - Gut …, 2020 - Taylor & Francis
The link between gut microbiota and the development of colorectal cancer has been
investigated. An imbalance in the gut microbiota promotes the progress of colorectal …

The role of gut barrier dysfunction and microbiome dysbiosis in colorectal cancer development

F Genua, V Raghunathan, M Jenab… - Frontiers in …, 2021 - frontiersin.org
Accumulating evidence indicates that breakdown of the+ protective mucosal barrier of the
gut plays a role in colorectal cancer (CRC) development. Inflammation and oxidative stress …

Relationship between VEGF family members, their receptors and cell death in the neoplastic transformation of colorectal cancer

D Dakowicz, M Zajkowska, B Mroczko - International journal of molecular …, 2022 - mdpi.com
Colorectal cancer (CRC) is the second most common cause of cancer death in the world.
Both modifiable and nonmodifiable risk factors play a significant role in the pathogenesis of …