Natural products have been an invaluable and useful source of anticancer agents over the
years. Several compounds have been synthesized from natural products by modifying their …

Cancer is the second leading cause of human death globally. PI3K/Akt/mTOR signaling is
one of the most frequently dysregulated signaling pathways observed in cancer patients that …

Flavonoids, commonly found in various plants, are a class of polyphenolic compounds
having a basic structural unit of 2-phenylchromone. Flavonoid compounds have attracted …

Cancer is a major public health concern in both developed and developing countries.
Several plant-derived anti-cancer agents including taxol, vinblastine, vincristine, the …

Due to the promising features of the ancient herbal plant Artemisia, its biologic activity has
been investigated for use in modern medicine. In this regard, Artemisia and its active …

Cancer is one of the biggest challenges facing medicine and its cure is regarded to be the
Holy Grail of medicine. Therapy in cancer is consisted as various artificial cytotoxic agents …

Chalcones are precursors of flavonoid biosynthesis in plants. Both flavonoids and chalcones
are intensively investigated because of a large spectrum of their biological activities. Among …

Herbal medicines have been played an important role in the human civilization since very
ancient time as a food, cloth, medicine and other aspects. Some of the important drugs in the …

Sphingolipid metabolites, such as ceramide, sphingosine and sphingosine-1-phosphate
(S1P), play many important roles in cellular activities. Ceramide and sphingosine inhibit cell …

In recent years, natural products have increasingly attracted more attention because of their
potential anticancer activity and low intrinsic toxicity. Hispidulin is a natural flavonoid with a …