Collagen type I is the main organic constituent of the bone extracellular matrix and has been
used for decades as scaffolding material in bone tissue engineering approaches when …

Bone tissue engineering utilizes three critical elements–cells, scaffolds, and bioactive factors–
to recapitulate the bone tissue microenvironment, inducing the formation of new bone …

Our goal was to generate functionalized 3D-printed scaffolds for bone regeneration using
silk-hydroxyapatite bone cements and osteoinductive, proangiogenic and neurotrophic …

Bone diseases, such as bone defects, cartilage damage, osteomyelitis, and osteoporosis,
are a primary focus area in current research. Cellulose and its derivatives, the most …

The growing interest in multi-functional metallic biomaterials for bone substitutes challenges
the current additive manufacturing (AM,= 3D printing) technologies. It is foreseeable that …

Traumatic, tumoral, and infectious bone defects are common in clinics, and create a big
burden on patient's families and society. Calcium phosphate (CaP)-based biomaterials have …

Large bone defects resulting from musculoskeletal tumours, infections, or trauma are often
unable to heal spontaneously. The challenge for surgeons is to avoid amputation, and …

Large bone defects with limited intrinsic regenerative potential represent a major surgical
challenge and are associated with a high socio-economic burden and severe reduction in …

Masquelet's induced membrane technique (MIMT) is a relatively new, two‐stage surgical
procedure to reconstruct segmental bone defects. First performed by Dr. Masquelet in the …

With the gradual demographic shift toward an aging and obese society, an increasing
number of patients are suffering from bone and cartilage injuries. However, conventional …