The Potential Use of Peptides in the Fight against Chagas Disease and Leishmaniasis
Parasitic diseases are among the most serious public health problems in developing
countries, causing high mortality and economic burdens. The Trypanosomatidae family …
countries, causing high mortality and economic burdens. The Trypanosomatidae family …
[PDF][PDF] Consequential drug combinations for tuberculosis treatments
CJ Pyle, DM Tobin - Cell Systems, 2021 - cell.com
Improved therapies for tuberculosis will require the careful revision of complex, multi-drug
regimens. In this issue of Cell Systems, Larkins-Ford et al. integrate extensive dose …
regimens. In this issue of Cell Systems, Larkins-Ford et al. integrate extensive dose …
[图书][B] PKPD-Model Based Preclinical Characterization of the Activity of Spectinamide 1599 Against Mycobacterial Subpopulations and the Identification of Potential …
ZH Temrikar - 2023 - search.proquest.com
Tuberculosis is one of the top 10 causes of death worldwide and the leading cause of death
from a single infectious agent prior to COVID19. Mycobacterium tuberculosis (Mtb) is the …
from a single infectious agent prior to COVID19. Mycobacterium tuberculosis (Mtb) is the …
Transcriptome signature of cell viability predicts drug response and drug interaction for Tuberculosis
V Srinivas, RA Ruiz, M Pan, SR Christinal Immanuel… - bioRxiv, 2021 - biorxiv.org
The treatment of tuberculosis (TB), which kills 1.8 million each year, remains difficult,
especially with the emergence of multidrug resistant strains of Mycobacterium tuberculosis …
especially with the emergence of multidrug resistant strains of Mycobacterium tuberculosis …
In vitro Methods to Better Evaluate Drug Responses in Cancer
H Schwartz - 2022 - repository.escholarship.umassmed …
Evaluating anti-cancer drugs in vitro is an important aspect of the drug development
pipeline. When evaluating anti-cancer drugs, two different measurements are used: relative …
pipeline. When evaluating anti-cancer drugs, two different measurements are used: relative …
RNA-based vaccine demonstrates prophylactic efficacy against Mycobacterium tuberculosis challenge in a mouse model
SE Larsen, JH Erasmus, VA Reese, T Pecor, J Archer… - bioRxiv, 2022 - biorxiv.org
Mycobacterium tuberculosis (Mtb) is an opportunistic bacterial pathogen that causes
tuberculosis disease (TB) and exerts an extensive burden on global health. The complex …
tuberculosis disease (TB) and exerts an extensive burden on global health. The complex …
[图书][B] Chemical Biology and Genetic Studies Targeting the Mycobacterial Cell Envelope
JT Williams - 2021 - search.proquest.com
Mycobacterium tuberculosis is one of the leading causes of death due to a single infectious
pathogen. The evolution and spread of drug resistant strains requires new antibiotics to …
pathogen. The evolution and spread of drug resistant strains requires new antibiotics to …
[PDF][PDF] A continuous epistasis model for predicting growth rate given combinatorial variation in gene expression and environment
KA Reynolds - scholar.archive.org
The ability to predict changes in cellular growth rate given variation in gene expression is
critical to interpret disease-causing mutations, engineer biosynthetic pathways, and …
critical to interpret disease-causing mutations, engineer biosynthetic pathways, and …
Hydrolysis or Cyclization of ATP: Regulating Cholesterol Utilization in Mycobacterium tuberculosis
KM Wilburn - 2021 - search.proquest.com
Tuberculosis remains a major cause of human morbidity and mortality, and is caused by
infection with the bacterium Mycobacterium tuberculosis. For thousands of years, M …
infection with the bacterium Mycobacterium tuberculosis. For thousands of years, M …